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Results for "

autonomic nervous systems

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Biochemical Assay Reagents

4

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2847
    Urocortin II, mouse

    		CRFR Metabolic Disease Endocrinology
    Urocortin II, mouse is a potent and selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor with Ki values of 0.66 nM and ﹥100 nM for CRFR2 and CRFR1, respectively. Urocortin II, mouse activates CRF2 receptors in a cAMP/PKA- and Ca 2+/CaMKII-dependent manner.Urocortin II, mouse is expressed in discrete areas of the central nervous system, and activates central neurons involved in the processing of visceral sensory information, and in modulating autonomic outflow .
    Urocortin II, mouse
  • HY-P1248
    Neuropeptide FF

    NPFF

    		 Neuropeptide FF Receptor Cardiovascular Disease Neurological Disease
    Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, is a NPFF1 and NPFF2 receptors agonist with Ki values of 2.82 nM and 0.21 nM, respectively. Neuropeptide FF induces abstinence syndrome, exerts antiopioid and analgesic effects, releases via calcium-dependent mechanisms from rat spinal cord, regulates memory, autonomic function, and neuroendocrine function, modulates pain and opioid antinociception, reduces food intake, stimulates water intake, alters cardiovascular parameters, and shows differential activity in hypothalamic paraventricular nucleus neurons. Neuropeptide FF is present in mammalian central nervous system and periphery, with NPFF-immunoreactivity increases in rat cerebrospinal fluid during opiate tolerance, and its NPFF gene and NPFF-R2 gene are up-regulated in rat spinal cord and dorsal root ganglia during peripheral inflammation. Neuropeptide FF can be used for the research of opioid tolerance, morphine-induced analgesia, abstinence syndrome, pain, hypertension, nociception, inflammatory pain, and neuropathic pain .
    Neuropeptide FF
  • HY-P1317A
    Nociceptin (1-13), amide TFA

    		Opioid Receptor Neurological Disease
    Nociceptin (1-13), amide TFA is a potent ORL1 receptor (opioid receptor-like 1 receptor, OP4) agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes .
    Nociceptin (1-13), amide TFA
  • HY-111025
    Ectylurea

    		Others Neurological Disease
    Ectylurea, a N-acylurea, can be used in studies of tension and anxiety symptoms, has no effect on the autonomic nervous system, and has no convulsive, analgesic or antispasmodic activity in animals .
    Ectylurea
  • HY-W015160
    1-(3-Methylbenzyl)piperazine

    		Drug Derivative Neurological Disease
    1-(3-Methylbenzyl)piperazine is a derivative of Benzylpiperazine that affects the central and the autonomic nervous systems, the blood pressure, and smooth muscle .
    1-(3-Methylbenzyl)piperazine
  • HY-106780
    Ecabapide

    DQ 2511

    		 Biochemical Assay Reagents Neurological Disease
    Ecabapide (DQ 2511) is an orally active gastroprokinetic agent. Ecabapide can ameliorate gastric emptying of stroke-prone spontaneously hypertensive rat model. Ecabapide can be studied in research on autonomic nervous system disorder .
    Ecabapide
  • HY-168571
    BTF

    		Orexin Receptor (OX Receptor) Neurological Disease
    BTF shows a selective binding affinity for OX1R with the Ki values of 2.33 nM and 62.8 nM of OX1R and OX2R, respectively .
    BTF
  • HY-B1661
    Hexamethonium chloride

    Hexone chloride

    		 Biochemical Assay Reagents Cardiovascular Disease Others
    Hexamethonium Chloride Dihydrate is a synthetic organic compound commonly used as a ganglion blocking agent, which means it blocks the transmission of nerve impulses between ganglion cells in the autonomic nervous system. Hexamethonium Chloride Dihydrate is used in various medical applications such as lowering blood pressure or inhibiting certain types of neuropathic pain. It works by inhibiting the release of acetylcholine, a neurotransmitter that plays a key role in regulating many bodily functions.
    Hexamethonium chloride
  • HY-P1317
    Nociceptin (1-13), amide

    		Opioid Receptor Neurological Disease
    Nociceptin (1-13)，amide is a potent ORL1 receptor (opioid receptor-like 1 receptor，OP4) agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes .
    Nociceptin (1-13), amide

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