1. GPCR/G Protein Neuronal Signaling
  2. Opioid Receptor
  3. Nociceptin (1-13), amide

Nociceptin (1-13), amide is a potent ORL1 receptor (opioid receptor-like 1 receptor, OP4) agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes.

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Nociceptin (1-13), amide Chemical Structure

Nociceptin (1-13), amide Chemical Structure

CAS No. : 178064-02-3

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Description

Nociceptin (1-13), amide is a potent ORL1 receptor (opioid receptor-like 1 receptor, OP4) agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes[1][2].

IC50 & Target

Ki: 0.75 nM (binding to rat forebrain membranes)[1]
pEC50: 7.9 (in mouse vas deferens)[2]

In Vivo

ORL1受体激动剂

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1381.59

Formula

C61H100N22O15

CAS No.
Sequence Shortening

FGGFTGARKSARK-NH2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Nociceptin (1-13), amide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Nociceptin (1-13), amide
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HY-P1317
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