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United States

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Cat. No.: HY-168571

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BTF

BTF shows a selective binding affinity for OX1R with the K_i values of 2.33 nM and 62.8 nM of OX1R and OX2R, respectively.

For research use only. We do not sell to patients.

Formula: C₂₂H₂₁FN₆OS
Molecular Weight:436.51

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

BTF Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BTF shows a selective binding affinity for OX1R with the K_i values of 2.33 nM and 62.8 nM of OX1R and OX2R, respectively^[1].

All Orexin Receptor (OX Receptor) Isoforms :

Chemical Information

Molecular Weight 436.51
Formula C₂₂H₂₁FN₆OS
SMILES

O=C(C1=CC(F)=CC=C1N2N=CC=N2)N([C@H](C3)C)CCCN3C4=NC5=CC=CC=C5S4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ishizaka Y, et al. Structure-Affinity-Pharmacokinetics Relationships of Novel 18F-Labeled 1,4-Diazepane Derivatives for Orexin 1 Receptor Imaging. J Med Chem. Published online October 21, 2024. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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BTF

All Orexin Receptor (OX Receptor) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BTF Related Classifications

HY-168571 Related Classifications