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Results for "

murine IgG1

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Peptides

8

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99023
    Girentuximab
    1 Publications Verification

    G250; cG250

    Carbonic Anhydrase Cancer
    Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX), a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC) .
    Girentuximab
  • HY-108852

    CHI 621

    Interleukin Related Infection Neurological Disease Inflammation/Immunology Cancer
    Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation .
    Basiliximab
  • HY-P99611

    64G12

    IFNAR Inflammation/Immunology
    Faralimomab (64G12) is an immunomodulator, and a murine anti-IFNA1 IgG1 mAb .
    Faralimomab
  • HY-P991608

    7F11C7

    Mucin Cancer
    CTM01 is a murine IgG1 (or humanized IgG4) monoclonal antibody inhibitor targeting MUC1. CTM01 has a broad spectrum anticancer activity against solid tumors of epithelial origin, such as breast, lung and ovarian cancer .
    CTM01
  • HY-P11905

    Biochemical Assay Reagents Others
    FcIII peptide is a 13-amino-acid peptide that competitively binds the hinge region of IgG Fc fragment with high affinity. FcIII peptide has an inhibition constant Ki of 25 nM when competing with Protein A for binding sites. FcIII peptide displays high selectivity toward human IgG subtypes yet weak binding affinity for murine IgG1. FcIII peptide anchors IgG Fc through hydrophobic interactions formed by tryptophan and valine residues, alongside multiple hydrogen bonds and salt bridges. FcIII peptide alters the local microenvironment of conjugated fluorescein after binding IgG Fc, which triggers enhanced fluorescent signals. FcIII peptide can be applied to researches related to monoclonal antibody production. .
    FcIII peptide
  • HY-P991815

    Transmembrane Glycoprotein Inflammation/Immunology
    Anti-Mouse CD90.1 Antibody (OX-7) reacts with the mouse and rat CD90.1. CD90 is present on a variety of cell types in murine and rat, including lymphatic vessels, T cells, neurons and fibroblasts. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977) .
    Anti-Mouse CD90.1 Antibody (OX-7)
  • HY-P992053

    Integrin Inflammation/Immunology
    Anti-CD11a Antibody (MHM24) is a monoclonal antibody targeting murine CD11a. Anti-CD11a Antibody (MHM24) binds to high-affinity (open) and low-affinity (closed) conformations of the αL subunit of LFA-1, and functionally blocks LFA-1-mediated interactions. Anti-CD11a Antibody (MHM24) blocks ICAM-1 binding to LFA-1-expressing cells. Anti-CD11a Antibody (MHM24) inhibits adhesion of high-affinity LFA-1-expressing cells to keratinocytes. Anti-CD11a Antibody (MHM24) inhibits PHA-induced lymphocyte proliferation. Anti-CD11a Antibody (MHM24) can be used for the research of inflammatory and autoimmune diseases. Recommend Isotype Controls: mouse IgG1 kappa, Isotype Control (HY-P99977) .
    Anti-CD11a Antibody (MHM24)

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