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platelet glycoprotein (GP) IIb/IIIa receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Glycoprotein VI (1) P-glycoprotein (1) Integrin (4)
By Research Areas:	Cardiovascular Disease (6)

Inhibitors & Agonists

Inhibitory Antibodies

Antibodies

Targets Recommended: Transmembrane Glycoprotein Platelet-activating Factor Receptor (PAFR) Glycoprotein VI PDGFR P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P9934

Abciximab 2 Publications Verification C7E3	Integrin	Cardiovascular Disease
Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a **glycoprotein (GP) IIb/IIIa** inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors .

HY-10307

Roxifiban	Integrin	Cardiovascular Disease
Roxifiban is a **platelet glycoprotein (GP) IIb/IIIa receptor** inhibitor that can be used in the study of angina .

HY-10313

ZD 2486	Integrin	Cardiovascular Disease
ZD 2486 is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist. ZD 2486 inhibits platelet aggregation by blocking the binding of fibrinogen to the GP IIb/IIIa receptor on platelets. ZD 2486 can be used for the study of conditions related to unwanted platelet aggregation, such as acute coronary syndrome, unstable angina pectoris, acute myocardial infarction, and complications from cardiovascular interventional procedures ^[1]

HY-10307A

Roxifiban acetate DMP 754	Integrin	Cardiovascular Disease
Roxifiban (acetate) is the acetate form of Roxifiban (HY-10307). Roxifiban (acetate) is a **platelet glycoprotein (GP) IIb/IIIa receptor** inhibitor that can be used in research related to angina .

HY-125615

DMP 728 methanesulfonate	Glycoprotein VI	Cardiovascular Disease Others
DMP 728 methanesulfonate is a platelet glycoprotein (GP) IIb/IIIa receptor antagonist. DMP 728 methanesulfonate shows dose-dependent antiplatelet and antithrombotic effects. DMP 728 methanesulfonate can be used in the study of effective antithrombotic agents in thromboembolic diseases of coronary and peripheral arteries .

HY-106394

TP-9201	P-glycoprotein	Cardiovascular Disease
TP-9201 is a platelet *glycoprotein* (GP) IIb/IIIa receptor antagonist. TP-9201 inhibits the interaction between GPIIb/IIIa and fibrinogen, thereby suppressing platelet aggregation. TP-9201 exhibits similar inhibitory activity on adenosine diphosphate (ADP) (HY-W010918)-induced platelet aggregation in humans, baboons, and dogs (IC₅₀ = 1-3 μM), while showing lower activity in rabbits (IC₅₀ = 45 μM) and rats (IC₅₀ = 20 μM). TP-9201can be used in studies related to the prevention of rethrombosis after arterial thrombolysis .

Cat. No.	Product Name	Target	Research Area	Image

HY-P9934

Abciximab 2 Publications Verification C7E3	Integrin	Cardiovascular Disease
Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a **glycoprotein (GP) IIb/IIIa** inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors .

Host:	Mouse (2) Rabbit (1)
Reactivity:	Human (2) Mouse (1)
Application:	IHC-P (1) ICC/IF (1) WB (2) FC (3)
Isotype:	IgG (1) IgG1 (2)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86724

	CD41 Antibody (YA6416) platelet glycoprotein IIb of IIb/IIIa complex; Integrin, alpha 2b(platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GPIIb; GTA; HPA3; CD 41; CD41 antigen; CD41a; CD41b; GP2b; GPalpha IIb; GPalphaIIb; Integrin alpha IIb; Integrin alpha IIb precursor; ITGA 2B; Integrin alpha 2b; ITGAB; platelet fibrinogen receptor alpha; platelet fibrinogen receptor alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet specific antigen bak; ITA2B_HUMAN.	WB, FC	Human
	CD41 Antibody (YA6416) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD41.

HY-P86724A

	CD41 Antibody (YA6416)(PBS only) platelet glycoprotein IIb of IIb/IIIa complex; Integrin, alpha 2b(platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GPIIb; GTA; HPA3; CD 41; CD41 antigen; CD41a; CD41b; GP2b; GPalpha IIb; GPalphaIIb; Integrin alpha IIb; Integrin alpha IIb precursor; ITGA 2B; Integrin alpha 2b; ITGAB; platelet fibrinogen receptor alpha; platelet fibrinogen receptor alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet specific antigen bak; ITA2B_HUMAN.	WB, FC	Human
	CD41 Antibody (YA6416) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD41.

HY-P86806

	CD41 Antibody (YA6499) antigen CD41 antibody; BDPLT16 antibody; BDPLT2 antibody; CD41 antibody; CD41B antibody; form 2 antibody; GP2B antibody; GPalpha IIb antibody; GPIIb antibody; GT antibody; antigen CD41 antibody; BDPLT16 antibody; BDPLT2 antibody; CD41 antibody; CD41B antibody; form 2 antibody; GP2B antibody; GPalpha IIb antibody; GPIIb antibody; GT antibody; GTA antibody; HPA3 antibody; Integrin alpha 2b antibody; Integrin alpha IIb antibody; Integrin alpha-IIb light chain antibody; Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) antibody; ITA2B_HUMAN antibody; Itga2b antibody; ITGAB antibody; platelet fibrinogen receptor, alpha subunit antibody; platelet glycoprotein IIb of IIb/IIIa complex antibody; platelet membrane glycoprotein IIb antibody; platelet specific antigen BAK antibody; PPP1R93 antibody;	IHC-P, FC, ICC/IF	Mouse
	CD41 Antibody (YA6499) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD41.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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