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Results for "

protoberberine

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-118581
    Coralyne chloride

    		Topoisomerase Cancer
    Coralyne chloride is a protoberberine alkaloid with potent anti-cancer activities. Coralyne chloride acts as a potent topoisomerase I poison and induces Top I mediated DNA cleavage . Coralyne chloride can be used for preparing coralyne derivatives as DNA binding fluorescent probes .
    Coralyne chloride
  • HY-N8346
    8-Oxocoptisine

    		Others Cancer
    8-Oxocoptisine is a natural protoberberine alkaloid with anti-cancer activity .
    8-Oxocoptisine
  • HY-N6865
    Groenlandicine

    		Topoisomerase Metabolic Disease Cancer
    Groenlandicine is a protoberberine alkaloid isolated from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR) . Groenlandicine selectively induces topoisomerase I-mediated DNA cleavage .
    Groenlandicine
  • HY-N6957
    8-Keto-berberine

    		Others Metabolic Disease
    8-Keto-berberine (compound 29) is a non-naturally occurring 11, 12-oxygenated protoberberine derived from naturally occurring 9, 10-oxygenated protoberberine .
    8-Keto-<em>berberine</em>

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