1. Cell Cycle/DNA Damage
  2. Topoisomerase
  3. Groenlandicine

Groenlandicine 

Cat. No.: HY-N6865 Purity: 99.69%
Handling Instructions

Groenlandicine is a protoberberine alkaloid isolated from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Groenlandicine selectively induces topoisomerase I-mediated DNA cleavage.

For research use only. We do not sell to patients.

Groenlandicine Chemical Structure

Groenlandicine Chemical Structure

CAS No. : 38691-95-1

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1 mg USD 190 In-stock
Estimated Time of Arrival: December 31
5 mg USD 571 In-stock
Estimated Time of Arrival: December 31
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Description

Groenlandicine is a protoberberine alkaloid isolated from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR)[1]. Groenlandicine selectively induces topoisomerase I-mediated DNA cleavage[2].

IC50 & Target

Topoisomerase I

 

Molecular Weight

322.33

Formula

C₁₉H₁₆NO₄+

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

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Groenlandicine
Cat. No.:
HY-N6865
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