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Results for "

schistosomicidal activity

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0176
    Dihydroartemisinin
    40+ Cited Publications

    Dihydroqinghaosu; β-Dihydroartemisinin; Artenimol

    		 Parasite NF-κB Autophagy Reactive Oxygen Species (ROS) Drug Metabolite Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection .
    Dihydroartemisinin
  • HY-118495
    Cardol diene

    		Parasite Infection
    Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability .
    Cardol diene
  • HY-N7854
    Anacardic acid diene

    Anacardic acid 15:2

    		 Bacterial Infection
    Anacardic acid diene is a polyunsaturated form of anacardic acid (HY-N2020) that has been found in cashew nut shell liquid. It has antibacterial activity against methicillin resistant S. aureus (MRSA) and S. mutans (MICs=12.5 and 6.25 μg/mL, respectively). Anacardic acid diene has schistosomicidal activity against adult S. mansoni worms when used at a concentration of 100 μM. It also inhibits soybean lipoxygenase-1 in a time-dependent manner.
    Anacardic acid diene
  • HY-W658325
    P-Decyloxyaniline

    		Drug Derivative Others
    P-Decyloxyaniline is a monoamine with one ether bond. P-Decyloxyaniline shows no activity against Schistosoma mansoni and does not exhibit schistosomicidal activity in infected mice; it also has oral toxicity, with an LD50 of 1.5 g/kg in mice .
    P-Decyloxyaniline
  • HY-23317
    N-Methyl-4-(8-phenoxyoctoxy)aniline

    		Parasite Infection
    N-Methyl-4-(8-phenoxyoctoxy) aniline (Compound 3568) is an anti-schistosomal agent. N-Methyl-4-(8-phenoxyoctoxy) aniline exhibits definite anti-Schistosoma mansoni activity in mouse models, but has high acute toxicity. N-Methyl-4-(8-phenoxyoctoxy) aniline can be used in studies related to schistosomiasis .
    N-Methyl-4-(8-phenoxyoctoxy)aniline
  • HY-N0176S6
    Dihydroartemisinin-d

    Dihydroqinghaosu-d; β-Dihydroartemisinin-d; Artenimol-d

    		 Isotope-Labeled Compounds Parasite NF-κB Autophagy Reactive Oxygen Species (ROS) Drug Metabolite Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Dihydroartemisinin-d (Dihydroqinghaosu-d) is the deuterium labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection.
    Dihydroartemisinin-d

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