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Cat. No.: HY-N0176S6

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Dihydroartemisinin-d

(Synonyms: Dihydroqinghaosu-d; β-Dihydroartemisinin-d; Artenimol-d)

Dihydroartemisinin-d (Dihydroqinghaosu-d) is the deuterium labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection.

For research use only. We do not sell to patients.

CAS No.: 252043-36-0
Formula: C₁₅H₂₃DO₅
Molecular Weight:285.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Dihydroartemisinin-d Chemical Structure

CAS No.: 252043-36-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
Calculators
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Bioz

Biological Activity

Description

All NF-κB Isoforms :

All Parasite Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 252043-36-0
Unlabeled Cas 71939-50-9
Molecular Weight 285.35
Formula C₁₅H₂₃DO₅
SMILES

O[C@]1([2H])[C@H](C)[C@]2([H])CC[C@@H](C)[C@]3([H])CC[C@@](O4)(C)OO[C@]32[C@]4([H])O1
Synonyms

Dihydroqinghaosu-d; β-Dihydroartemisinin-d; Artenimol-d
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.