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Dihydroartemisinin

(Synonyms: Dihydroqinghaosu; β-Dihydroartemisinin; Artenimol)
45 Cited Publications
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Based on 45 publication(s) in Google Scholar

Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection.

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  • Pureza: 98.0%
  • No. CAS: 71939-50-9
  • Fòrmula: C15H24O5
  • Peso molecular:284.35
  • Almacenamiento:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 2 years , -20°C, 1 year
  • Dihydroartemisinin Chemical Structure
    Dihydroartemisinin Chemical Structure
  • Experimental Validation Results for Dihydroartemisinin
  • Experimental Validation Results for Dihydroartemisinin
  • Experimental Validation Results for Dihydroartemisinin
  • Experimental Validation Results for Dihydroartemisinin
No. CAS: 71939-50-9
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  • Dihydroartemisinin Chemical Structure
    Dihydroartemisinin Chemical Structure
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  • 1/16

    Dihydroartemisinin purchased from MedChemExpress. Usage Cited in: Kaohsiung J Med Sci. 2023 Jul;39(7):699-709. [Abstract]

    Customer Validation
     Dihydroartemisinin (DHA; 12.5, 25, 50 μM; 24 h) significantly reduces the viability of A549-GR cells in a dose-dependent manner.

  • 1/16

    Dihydroartemisinin purchased from MedChemExpress. Usage Cited in: Kaohsiung J Med Sci. 2023 Jul;39(7):699-709. [Abstract]

    Customer Validation
     Dihydroartemisinin (DHA; 12.5, 25, 50 μM; 24 h) increases the expression of cleaved-Caspase 3, but decreases the expression of PARP and Bcl-2 in A549-GR cells.

  • 1/16

    Dihydroartemisinin purchased from MedChemExpress. Usage Cited in: Oxid Med Cell Longev. 2023 Feb 16:2023:9595201. [Abstract]

    Customer Validation
     Dihydroartemisinin (DHA; 50, 100 µM) remarkably inhibits single-cell colony formation of HSC3 cells and SAS cells in a dosage-dependent manner (Fig e and f).

  • 1/16

    Dihydroartemisinin purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2018 Jun 27;501(3):636-642. [Abstract]

    Customer Validation
     Immunoblot analysis of the expression levels of BCL-2 and BAX after treatment of HCT116 TP53-/- cells with 20 μM 5-FU and 1.25 μM DHA alone or in combination for 48 h. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) served as a loading control.

  • Dihydroartemisinin