Search Result

Results for "

sonic+hedgehog+shh

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (4) Bacterial (4) Fluorescent Dye (1) Hedgehog (8) Isotope-Labeled Compounds (2) Parasite (4) Reference Standards (1)
By Research Areas:	Cancer (7) Infection (4) Inflammation/Immunology (1)

Inhibitors & Agonists

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0508

Ornidazole 2 Publications Verification Ro 7-0207	Bacterial Parasite Antibiotic Hedgehog	Infection Cancer
Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits *Sonic hedgehog* (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .

HY-100515

Robotnikinin 3 Publications Verification	Hedgehog	Inflammation/Immunology
Robotnikinin is a small molecule capable of binding to and inhibiting the activity of *Sonic Hedgehog (Shh)* signaling up stream of Smo .

HY-158059

DS-1-38	Hedgehog	Cancer
DS-1-38 is an EYA1 antagonist that blocks Sonic Hedgehog (SHH) signaling. EYA1 is a haloacid dehalogenase phosphatase and transcription factor that regulates tumorigenesis and proliferation in SHH medulloblastoma (SHH-MB) .

HY-B0508S1

Ornidazole-13C2,15N2 Ro 7-0207-¹³C₂,¹⁵N₂	Isotope-Labeled Compounds Bacterial Parasite Antibiotic Hedgehog	Infection
Ornidazole- ¹³C₂, ¹⁵N₂ is the ¹³C, ¹⁵N labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits *Sonic hedgehog* (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .

HY-120664

BRD50837	Hedgehog	Cancer
BRD50837 is a potent inhibitor of *Sonic Hedgehog (Shh), with the EC₅₀* of 0.09 μM. BRD50837 plays an important role in cancer research .

HY-B0508S

Ornidazole-d5 Ro 7-0207-d₅	Isotope-Labeled Compounds Bacterial Parasite Antibiotic Hedgehog	Infection Cancer
Ornidazole-d₅ is deuterium labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits *Sonic hedgehog* (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .

HY-116455

BRD-9526	Fluorescent Dye	Cancer
BRD-9526 is a potent and selective Sonic Hedgehog (Shh) pathway inhibitor with potential anti-cancer activity. The mechanism of BRD-9526 is similar in some ways to commonly used inhibitors such as cyclopamine, but is significantly different in other ways. The discovery of BRD-9526 may provide a useful probe for studying complex signaling pathways .

HY-B0508R

Ornidazole (Standard) Ro 7-0207 (Standard)	Reference Standards Bacterial Parasite Antibiotic Hedgehog	Infection Cancer
Ornidazole (Standard) is the analytical standard of Ornidazole. This product is intended for research and analytical applications. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits *Sonic hedgehog* (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .

HY-P992409

MEDI-5304	Hedgehog	Cancer
MEDI-5304 is a *hedgehog* antibody inhibitor with human *sonic hedgehog* (SHH) K_D of 5.13 pmol/L, and human Indian hedgehog (IHH) K_D of 34.7 pmol/L. MEDI-5304 binds and neutralizes SHH and IHH, blocks downstream target gene transcription, inhibits osteoblast differentiation. MEDI-5304 can be used for the research of colon cancer .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992409

MEDI-5304	Hedgehog	Cancer
MEDI-5304 is a *hedgehog* antibody inhibitor with human *sonic hedgehog* (SHH) K_D of 5.13 pmol/L, and human Indian hedgehog (IHH) K_D of 34.7 pmol/L. MEDI-5304 binds and neutralizes SHH and IHH, blocks downstream target gene transcription, inhibits osteoblast differentiation. MEDI-5304 can be used for the research of colon cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0508

Ornidazole 2 Publications Verification Ro 7-0207	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Parasite Antibiotic Hedgehog
Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits *Sonic hedgehog* (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .

HY-B0508R

Ornidazole (Standard) Ro 7-0207 (Standard)	Structural Classification Microorganisms Antibiotics Antibacterial Disease Research Other Antibiotics Source Classification	Reference Standards Bacterial Parasite Antibiotic Hedgehog
Ornidazole (Standard) is the analytical standard of Ornidazole. This product is intended for research and analytical applications. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits *Sonic hedgehog* (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .

Cat. No.	Product Name	Chemical Structure

HY-B0508S1

Ornidazole-13C2,15N2
Ornidazole- ¹³C₂, ¹⁵N₂ is the ¹³C, ¹⁵N labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits *Sonic hedgehog* (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .

HY-B0508S

Ornidazole-d5
Ornidazole-d₅ is deuterium labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits *Sonic hedgehog* (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

We use cookies

MedChemExpress values your privacy and your trust is important to us. We use cookies to enhance your website experience. Some cookies are necessary to run the website. Privacy and Cookie Policy