TAMRA azide, 5-isomer

Name: TAMRA azide, 5-isomer
Brand: MedChemExpress
SKU: HY-151857
Rating: 4.5 (1 reviews)

Cat. No.: HY-151857 Pureza: 98.60%: Ficha de datos
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TAMRA azide, 5-isomer is a click chemical containing azide groups that can be used as a linker for TAMRA. The azide group of TAMRA Azide, 5-isomer enables copper-catalyzed click chemical reactions with alkynes, DBCO, and BCN. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups (Ex/Em = 555/580 nm).

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No. CAS : 825651-66-9

Tamaño	Stock	Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	En stock	Estimated Time of Arrival: December 31
Solid
1 mg	En stock	Estimated Time of Arrival: December 31
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
200 mg	Obtener un presupuesto
500 mg	Obtener un presupuesto

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Revisión del cliente

Based on 1 publication(s) in Google Scholar

1 Publications Citing Use of MCE TAMRA azide, 5-isomer

•iScience. 2025 May 2;28(6):112569. [Abstract]

Cell Imaging/Staining

: TAMRA azide, 5-isomer purchased from MedChemExpress. Usage Cited in: iScience. 2025 May 2;28(6):112569. [Abstract]; EdU incorporation was conducted at E14.5 for 1 h to see proliferating cells in S-phase (EdU) (4 control brains including 2 Atf6a^fl/flAtf6b^fl/fl embryos and 2 Atf6a^fl/flAtf6b^fl/+ embryos, and 4 dcKO brains). TAMRA azide, 5-isomer (5-TAMRA-Azide, 0.5 μM), was utilized as a dye in this experiment.

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Revisión del cliente

Descripciòn

TAMRA azide, 5-isomer is a click chemical containing azide groups that can be used as a linker for TAMRA. The azide group of TAMRA Azide, 5-isomer enables copper-catalyzed click chemical reactions with alkynes, DBCO, and BCN^[1]^[2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups (Ex/Em = 555/580 nm).

In Vitro

Click chemistry is used to describe the selective, modular, wide range and high-yield chemical reactions that allow rapid synthesis of new compounds through heteroatom linking (C-X-C). Bertozzi developed click chemistry in a new dimension —Bioorthogonal chemistry. It is defined as a rapid and selective reaction that does not interfere with biological processes under physiological conditions. Common reaction structures of click chemistry, such as Azide, Alkyne, DBCO, BCN, TCO and Tetrazine.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

512.56

Fòrmula

C₂₈H₂₈N₆O₄

No. CAS

825651-66-9

Appearance

Solid

Color

Brown to reddish brown

SMILES

[N-]=[N+]=NCCCNC(C1=CC(C([O-])=O)=C(C2=C3C=CC(N(C)C)=CC3=[O+]C4=C2C=CC(N(C)C)=C4)C=C1)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvente y solubilidad

In Vitro:

DMSO : 125 mg/mL (243.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9510 mL	9.7550 mL	19.5099 mL
5 mM	0.3902 mL	1.9510 mL	3.9020 mL
10 mM	0.1951 mL	0.9755 mL	1.9510 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureza y Documentación

Purity: 98.60%

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Ficha de datos (273 KB) SDS (252 KB)

COA (249 KB) HNMR (287 KB) RP-HPLC (293 KB) MS (177 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Willnow S, et al. A selenium-based click AdoMet analogue for versatile substrate labeling with wild-type protein methyltransferases. Chembiochem. 2012 May 29;13(8):1167-73. [Content Brief]

[2]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.9510 mL	9.7550 mL	19.5099 mL	48.7748 mL
	5 mM	0.3902 mL	1.9510 mL	3.9020 mL	9.7550 mL
	10 mM	0.1951 mL	0.9755 mL	1.9510 mL	4.8775 mL
	15 mM	0.1301 mL	0.6503 mL	1.3007 mL	3.2517 mL
	20 mM	0.0975 mL	0.4877 mL	0.9755 mL	2.4387 mL
	25 mM	0.0780 mL	0.3902 mL	0.7804 mL	1.9510 mL
	30 mM	0.0650 mL	0.3252 mL	0.6503 mL	1.6258 mL
	40 mM	0.0488 mL	0.2439 mL	0.4877 mL	1.2194 mL
	50 mM	0.0390 mL	0.1951 mL	0.3902 mL	0.9755 mL
	60 mM	0.0325 mL	0.1626 mL	0.3252 mL	0.8129 mL
	80 mM	0.0244 mL	0.1219 mL	0.2439 mL	0.6097 mL
	100 mM	0.0195 mL	0.0975 mL	0.1951 mL	0.4877 mL