2. PROTAC
  3. PROTAC Linkers
  4. tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate

tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate 

Cat. No.: HY-30756 Pureté: 99.89%
COA
SDS
Instruction de manipulation Technical Support

tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate is a PROTAC linker. tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate can be used in the synthesis of PROTAC ER Degrader-12 (HY-160264) and PROTAC AR Degrader-9 (HY-170332).

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tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate

tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate Chemical Structure

CAS No. : 236406-55-6

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Other Forms of tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate:

tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate Related Antibodies

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Description

tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate is a PROTAC linker. tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate can be used in the synthesis of PROTAC ER Degrader-12 (HY-160264) and PROTAC AR Degrader-9 (HY-170332)[1].

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate Related Antibodies
Masse moléculaire

226.32

Formule

C12H22N2O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1CC2(CCNCC2)C1)OC(C)(C)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

RT, protect from light

In solvent -80°C 1 year
-20°C 6 months
Pureté et documentation

Purity: 99.89%

SDS (394 KB)

COA (247 KB) HNMR (116 KB) MS (249 KB) GC (217 KB)

Instruction de manipulation (2659 KB)
Références
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tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate236406-55-6PROTAC LinkersPROTAC linkerPROTAC ER Degrader-12PROTAC AR Degrader-9Inhibitorinhibitorinhibit

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tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate
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