PROTAC ER Degrader-12
PROTAC ER Degrader-12 (Compound 70) is an estrogen receptor PROTAC degrader (DC50: <10 nM), and inhibits MCF-7 proliferation (DC50: <10 nM). PROTAC ER Degrader-12 has anticancer effect.
(Pink: Estrogen receptor ligand (HY-169978); Blue: Cereblon ligand (HY-138793); Black: linker (HY-30756)).
For research use only. We do not sell to patients.
- Formula: C47H48F3N5O5
- Molecular Weight:819.91
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTACs Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 819.91
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Formula C47H48F3N5O5
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SMILES
O=C(N(C1CCC(NC1=O)=O)C2)C3=C2C=C(C=C3)N(C4)CC4(CC5)CCN5CC(CC6)CCN6C7=CC=C([C@@H]8C(C=CC(O)=C9)=C9OC[C@@H]8C%10=C(F)C=CC=C%10F)C=C7F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)