Thiosemicarbazide

Name: Thiosemicarbazide
Brand: MedChemExpress
SKU: HY-Y0032
Rating: 4.5 (1 reviews)

Cat. No.: HY-Y0032 Pureza: 99.91%: Ficha de datos
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SDS
Instrucciones de manejo
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Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co(II) and Cu(I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals.

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Thiosemicarbazide Estructura química

No. CAS : 79-19-6

Tamaño	Stock	Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	En stock	Estimated Time of Arrival: December 31
Solid
5 g	En stock	Estimated Time of Arrival: December 31
10 g	En stock	Estimated Time of Arrival: December 31
50 g	En stock	Estimated Time of Arrival: December 31
100 g	En stock	Estimated Time of Arrival: December 31
> 100 g	Obtener un presupuesto

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Revisión del cliente

Based on 1 publication(s) in Google Scholar

Other Forms of Thiosemicarbazide:

Thiosemicarbazide (Standard) Obtener un presupuesto

1 Publications Citing Use of MCE Thiosemicarbazide

•PLoS Pathog. 2026 Jan 26;22(1):e1013903. [Abstract]

Recomendaciones destacadas

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

In Vivo

Thiosemicarbazide (20 μg/g, s.c.) induces abnormal behavior and convulsions in 1-day-old and 1-month-old guinea pigs ^[3].<
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MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

91.14

Fòrmula

CH₅N₃S

No. CAS

79-19-6

Appearance

Solid

Color

Off-white to yellow

SMILES

NNC(N)=S

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvente y solubilidad

In Vitro:

DMSO : 125 mg/mL (1371.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	10.9721 mL	54.8607 mL	109.7213 mL
5 mM	2.1944 mL	10.9721 mL	21.9443 mL
10 mM	1.0972 mL	5.4861 mL	10.9721 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureza y Documentación

Purity: 99.91%

Select Batch:

Ficha de datos (269 KB) SDS (479 KB)

COA (242 KB) HNMR (258 KB) RP-HPLC (255 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Yamashita J. Susceptibility to thiosemicarbazide (an antagonist of vitamin B6), and phylogenetic and ontogenetic development of brain. J Nutr Sci Vitaminol (Tokyo). 1974;20(2):113-9. [Content Brief]

[2]. Kozyra P, et al. Potential Anticancer Agents against Melanoma Cells Based on an As-Synthesized Thiosemicarbazide Derivative. Biomolecules. 2022 Jan 18;12(2):151. [Content Brief]

[3]. Hamrani O, et al. Reaction of thiosemicarbazide with some divalent ions: Synthesis, characterization, molecular modeling, and evaluation of the catalytic and biological activity of the complexes[J]. Inorganic and Nano-Metal Chemistry, 2017, 47(7): 1070-1079.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	10.9721 mL	54.8607 mL	109.7213 mL	274.3033 mL
	5 mM	2.1944 mL	10.9721 mL	21.9443 mL	54.8607 mL
	10 mM	1.0972 mL	5.4861 mL	10.9721 mL	27.4303 mL
	15 mM	0.7315 mL	3.6574 mL	7.3148 mL	18.2869 mL
	20 mM	0.5486 mL	2.7430 mL	5.4861 mL	13.7152 mL
	25 mM	0.4389 mL	2.1944 mL	4.3889 mL	10.9721 mL
	30 mM	0.3657 mL	1.8287 mL	3.6574 mL	9.1434 mL
	40 mM	0.2743 mL	1.3715 mL	2.7430 mL	6.8576 mL
	50 mM	0.2194 mL	1.0972 mL	2.1944 mL	5.4861 mL
	60 mM	0.1829 mL	0.9143 mL	1.8287 mL	4.5717 mL
	80 mM	0.1372 mL	0.6858 mL	1.3715 mL	3.4288 mL
	100 mM	0.1097 mL	0.5486 mL	1.0972 mL	2.7430 mL