2. Metabolic Enzyme/Protease
  3. Tyrosinase
  4. Tyrosinase-IN-5

Tyrosinase-IN-5 (compound 16c) is a potent inhibitor of tyrosinase with an IC50 of 0.02 μM. Tyrosinase-IN-5 efficiently suppresses the melanogenesis without significant toxicity on cells.

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Tyrosinase-IN-5

Tyrosinase-IN-5 Estructura química

No. CAS : 2525175-90-8

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Tyrosinase-IN-5 Related Antibodies

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Descripciòn

Tyrosinase-IN-5 (compound 16c) is a potent inhibitor of tyrosinase with an IC50 of 0.02 μM. Tyrosinase-IN-5 efficiently suppresses the melanogenesis without significant toxicity on cells[1].

Cellular Effect
Cell Line Type Value Description References
B16-F10 IC50
143.2 3
Compound: 16c
Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability by MTT assay
[PMID: 32652434]
B16-F10 IC50
143.2 3
Compound: 16c
Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability by MTT assay
[PMID: 32652434]
B16-F10 IC50
143.2 3
Compound: 16c
Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability by MTT assay
[PMID: 32652434]
HFF IC50
194.1 3
Compound: 16c
Cytotoxicity against human HFF cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human HFF cells assessed as reduction in cell viability by MTT assay
[PMID: 32652434]
HFF IC50
194.1 3
Compound: 16c
Cytotoxicity against human HFF cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human HFF cells assessed as reduction in cell viability by MTT assay
[PMID: 32652434]
HFF IC50
194.1 3
Compound: 16c
Cytotoxicity against human HFF cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human HFF cells assessed as reduction in cell viability by MTT assay
[PMID: 32652434]
Peso molecular

367.31

Fòrmula

C18H13N3O6
No. CAS
SMILES

O=C1C=C(OCC2=CN(CC3=CC(C(O)=CO3)=O)N=N2)C4=CC=CC=C4O1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

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Pureza y Documentación
Referencias
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Tyrosinase-IN-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tyrosinase-IN-52525175-90-8TyrosinasetyrosinasemelanogenesistoxicityInhibitorinhibitorinhibit

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Nombre del producto:
Tyrosinase-IN-5
Cat. No.:
HY-143459
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