UDP-glucosamine disodium

Name: UDP-glucosamine disodium
Brand: MedChemExpress
SKU: HY-139793
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Cat. No.: HY-139793: Ficha de datos
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UDP-glucosamine (UDP-GlcNAc) disodium is a substrate for O-GlcNAc transferase, which catalyzes the attachment of O-GlcNAc to proteins. O-GlcNAcase catalyzes the removal of O-GlcNAc from proteins. UDP-glucosamine (UDP-GlcNAc) disodium is the end product of the hexosamine biosynthesis pathway, which is regulated primarily by glucose-6-phosphate-Glutamine:fructose-6-phosphate amidotransferase (GFAT).

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UDP-glucosamine disodium Estructura química

No. CAS : 1355005-51-4

Tamaño	Stock	Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	Obtener un presupuesto	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	Obtener un presupuesto	Estimated Time of Arrival: December 31
Solid
1 mg	Obtener un presupuesto 3 - 5 weeks 2 - 4 weeks 4 - 6 weeks 2 - 4 weeks	Estimated Time of Arrival: December 31
5 mg	Obtener un presupuesto 3 - 5 weeks 2 - 4 weeks 4 - 6 weeks 2 - 4 weeks	Estimated Time of Arrival: December 31
10 mg	Obtener un presupuesto 3 - 5 weeks 2 - 4 weeks 4 - 6 weeks 2 - 4 weeks	Estimated Time of Arrival: December 31
50 mg	Obtener un presupuesto
100 mg	Obtener un presupuesto

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Based on 1 Customer Validation

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Referencias
Revisión del cliente

Descripciòn

Peso molecular

609.28

Fòrmula

C₁₅H₂₃N₃Na₂O₁₆P₂

No. CAS

1355005-51-4

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@](N2C(NC(C=C2)=O)=O)([H])O[C@@H]([C@H]1O)COP(OP(O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3N)O)O)CO)(O[Na])=O)(O[Na])=O

Structure Classification

Others

Initial Source

Endogenous metabolite

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

H₂O : 250 mg/mL (410.32 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6413 mL	8.2064 mL	16.4128 mL
5 mM	0.3283 mL	1.6413 mL	3.2826 mL
10 mM	0.1641 mL	0.8206 mL	1.6413 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureza y Documentación

Ficha de datos (272 KB) SDS (251 KB) Instrucciones de manejo (2659 KB)

Referencias

[1]. Chatham JC, Young ME, Zhang J. Role of O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins in diabetic cardiovascular complications. Curr Opin Pharmacol. 2021;57:1-12. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.6413 mL	8.2064 mL	16.4128 mL	41.0320 mL
	5 mM	0.3283 mL	1.6413 mL	3.2826 mL	8.2064 mL
	10 mM	0.1641 mL	0.8206 mL	1.6413 mL	4.1032 mL
	15 mM	0.1094 mL	0.5471 mL	1.0942 mL	2.7355 mL
	20 mM	0.0821 mL	0.4103 mL	0.8206 mL	2.0516 mL
	25 mM	0.0657 mL	0.3283 mL	0.6565 mL	1.6413 mL
	30 mM	0.0547 mL	0.2735 mL	0.5471 mL	1.3677 mL
	40 mM	0.0410 mL	0.2052 mL	0.4103 mL	1.0258 mL
	50 mM	0.0328 mL	0.1641 mL	0.3283 mL	0.8206 mL
	60 mM	0.0274 mL	0.1368 mL	0.2735 mL	0.6839 mL
	80 mM	0.0205 mL	0.1026 mL	0.2052 mL	0.5129 mL
	100 mM	0.0164 mL	0.0821 mL	0.1641 mL	0.4103 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.