Urotensin II, mouse TFA

Name: Urotensin II, mouse TFA
Brand: MedChemExpress
SKU: HY-P1483A
Rating: 4.5 (0 reviews)

Cat. No.: HY-P1483A Purity: 99.50%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Urotensin II, mouse TFA is an endogenous ligand for the orphan G-protein-coupled receptor GPR14 or SENR. Urotensin II, mouse TFA is a potent vasoconstrictor. Urotensin II, mouse TFA plays a physiological role in the central nervous system.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Custom Peptide Synthesis

Urotensin II, mouse TFA 화학구조

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	견적 받기
100 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of Urotensin II, mouse TFA:

Urotensin II, mouse acetate In-stock
Urotensin II, mouse 견적 받기

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

IC₅₀ & Target

GPR14^[1]

In Vivo

Urotensin II is a somatostatin-like cyclic peptide which functions as an arterial vasocontrictor, vasodilator, and bronchoconstriction mediator^[1].
Urotensin II (0.1 nmol, 0.3 nmol, and 3 nmol; intracerebroventricular administration) induces anxiogenic-like behaviors in the elevated plus maze test and the hole-board test in mice in a dose-dependent manner^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male C57BL/6N mice (8 weeks old)^[1]
Dosage:	0.1 nmol, 0.3 nmol, and 3 nmol
Administration:	Intracerebroventricular (i.c.v.) administration
Result:	Decreased the amount of head dipping without significant alteration of the motor activity.

분자량

1747.87

화학식

C₇₈H₁₀₁F₃N₁₈O₂₁S₂

Appearance

Solid

Color

White to off-white

선적

Room temperature in continental US; may vary elsewhere.

보관

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

H₂O : 50 mg/mL (28.61 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.5721 mL	2.8606 mL	5.7212 mL
5 mM	0.1144 mL	0.5721 mL	1.1442 mL
10 mM	0.0572 mL	0.2861 mL	0.5721 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (57.21 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.50%

Select Batch:

Data Sheet (275 KB) SDS (252 KB)

COA (252 KB) LCMS (98 KB) Elemental Analysis Report (103 KB)

Handling Instructions (2659 KB)

References

[1]. Matsumoto Y, et al. Intracerebroventricular administration of urotensin II promotes anxiogenic-like behaviors in rodents. Neurosci Lett. 2004 Mar 25;358(2):99-102. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.5721 mL	2.8606 mL	5.7212 mL	14.3031 mL
	5 mM	0.1144 mL	0.5721 mL	1.1442 mL	2.8606 mL
	10 mM	0.0572 mL	0.2861 mL	0.5721 mL	1.4303 mL
	15 mM	0.0381 mL	0.1907 mL	0.3814 mL	0.9535 mL
	20 mM	0.0286 mL	0.1430 mL	0.2861 mL	0.7152 mL
	25 mM	0.0229 mL	0.1144 mL	0.2288 mL	0.5721 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.