1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. β-Estradiol-6-CMO-PEG3-biotin

β-Estradiol-6-CMO-PEG3-biotin 

Cat. No.: HY-130929
Handling Instructions

β-Estradiol-6-CMO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

β-Estradiol-6-CMO-PEG3-biotin Chemical Structure

β-Estradiol-6-CMO-PEG3-biotin Chemical Structure

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Description

β-Estradiol-6-CMO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Molecular Weight

759.95

Formula

C₃₈H₅₇N₅O₉S

SMILES

C[[email protected]@]12[[email protected]](CC[[email protected]]2O)([H])[[email protected]@]3([H])[[email protected]](C(C=CC(O)=C4)=C4/C(C3)=N\OCC(NCCOCCOCCOCCNC(CCCC[[email protected]@H]5SC[[email protected]](N6)[[email protected]@H]5NC6=O)=O)=O)([H])CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

β-Estradiol-6-CMO-PEG3-biotinADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product name:
β-Estradiol-6-CMO-PEG3-biotin
Cat. No.:
HY-130929
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