β-Lactoglobulin

製品番号: HY-NP008 純度: 98%: Data Sheet SDS COA 取扱説明書
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β-Lactoglobulin, a major whey protein, is a small globular protein from the lipocalin family. β-Lactoglobulin is an important source of the essential and branched-chain amino acids (leucine, isoleucine, and valine). β-Lactoglobulin shows antioxidant properties, because it contains two disulfide bonds and one free thiol group. β-Lactoglobulin is a ligand transport agent. β-Lactoglobulin is one of the major allergens in milk and can be utilized in the research for developing safe hypoallergenic dairy products.

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β-Lactoglobulin 構造式

CAS 番号 : 9045-23-2

容量	価格（税別）	在庫状況	数量
100 mg	$35	在庫あり	Estimated Time of Arrival: December 31
500 mg	$70	在庫あり	Estimated Time of Arrival: December 31
1 g	$115	在庫あり	Estimated Time of Arrival: December 31
5 g	$288	在庫あり	Estimated Time of Arrival: December 31
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50 g		お問い合わせ

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Retinol Binding Protein

生物活性
純度とドキュメンテーション
参考文献
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製品説明	β-Lactoglobulin, a major whey protein, is a small globular protein from the lipocalin family. β-Lactoglobulin is an important source of the essential and branched-chain amino acids (leucine, isoleucine, and valine). β-Lactoglobulin shows antioxidant properties, because it contains two disulfide bonds and one free thiol group. β-Lactoglobulin is a ligand transport agent. β-Lactoglobulin is one of the major allergens in milk and can be utilized in the research for developing safe hypoallergenic dairy products^[1]^[2]^[3]^[4].
体外実験	Heat treatment of bovine milk antigen bovine β-Lactoglobulin generates ligands for RAGE, Gal-3, CD-36 and SR-AI as a result of structural changes and glycation. Glycated BLG is less sensitive to digestion and maintains its binding to RAGE and Gal-3. Post-digestion retained immunogenicity of glycated BLG may be mediated via RAGE as a signaling pathway, and via Gal-3 facilitating internalization^[1]. β-Lactoglobulin possesses antioxidant properties, because it contains two disulfide bonds (Cys-66 to Cys-160, Cys-106 to Cys-119) and one free thiol group (Cys-121)^[2]. Structurally, β-Lactoglobulin has unique features, i.e. a rigid β-barrel core surrounded by one long and several short α-helices with two disulfide (SS) bonds and one free cysteinyl thiol (SH) buried in the core. There are two variants of β-Lactoglobulin (BLG). Variant A (BLGA) has Asp64 and Val118 in place of Gly64 and Ala118 of another variant, B (BLGB). These variants are in equilibrium with a hetero- or homo-dimer under physiological conditions^[3]. β-Lactoglobulin is the building block of amyloid fibrils and has a variety of applications, including stabilizing gels or emulsions^[4]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. β-Lactoglobulin 関連抗体
CAS 番号	9045-23-2
Appearance	Solid
Color	White to off-white
SMILES	[b-Lactoglobulin]
輸送条件	Room temperature in continental US; may vary elsewhere.
保管条件	Please store the product under the recommended conditions in the Certificate of Analysis.
溶剤 & 溶解度	体外: H₂O : ≥ 5 mg/mL "≥" means soluble, but saturation unknown. Molarity Calculator Dilution Calculator Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Mass = Concentration × Volume × Molecular Weight Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final) 一般には略語で表示されます：C₁V₁ = C₂V₂ 濃度 _（開始） C1 × 体積 _（開始） V1 = 濃度 _（終了） C2 × 体積 _（終了） V2 In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kg Animal weight (per animal) g Dosing volume (per animal) μL Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Calculation results: Working solution concentration: mg/mL The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE). Tel: 609-228-6898 E-mail: [email protected] Technical Support: [email protected]
純度とドキュメンテーション	純度: 98% Select Batch: データシート (270 KB) SDS (251 KB) COA (231 KB) 取扱説明書 (2659 KB)
参考文献	[1]. Teodorowicz M, et al. Enhanced Uptake of Processed Bovine β-Lactoglobulin by Antigen Presenting Cells: Identification of Receptors and Implications for Allergenicity. Mol Nutr Food Res. 2021;65(8):e2000834. [Content Brief] [2]. Gołębiowski A, et al. Isolation and Self-Association Studies of Beta-Lactoglobulin. Int J Mol Sci. 2020;21(24):9711. Published 2020 Dec 19. [Content Brief] [3]. Iwaoka M, et al. Oxidative folding pathways of bovine milk β-lactoglobulin with odd cysteine residues. FEBS Open Bio. 2019;9(8):1379-1391. [Content Brief] [4]. Uttinger MJ, et al. Measurement of length distribution of beta-lactoglobulin fibrils by multiwavelength analytical ultracentrifugation. Eur Biophys J. 2020;49(8):745-760. [Content Brief]