15a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-26-oic acid

Art. -Nr.: HY-N8104 Reinheit: 97.78%: Data Sheet
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15a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-26-oic acid, a Lanostane triterpenoid, possesses NO production inhibitory activities of LPS-induced microglia.

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15a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-26-oic acid Chemische Struktur

CAS. Nr. : 1961358-01-9

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1 mg	Auf Lager	Estimated Time of Arrival: December 31
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Beschreibung

15a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-26-oic acid, a Lanostane triterpenoid, possesses NO production inhibitory activities of LPS-induced microglia^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
BV-2	IC₅₀	26.81 3 Compound: 2	Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs measured after 15 mins by Griess assay Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs measured after 15 mins by Griess assay	[PMID: 27335254]
BV-2	IC₅₀	26.81 3 Compound: 2	Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs measured after 15 mins by Griess assay Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs measured after 15 mins by Griess assay	[PMID: 27335254]
BV-2	IC₅₀	26.81 3 Compound: 2	Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs measured after 15 mins by Griess assay Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs measured after 15 mins by Griess assay	[PMID: 27335254]

Molekulargewicht

498.65

Formel

C₃₀H₄₂O₆

CAS. Nr.

1961358-01-9

Appearance

Solid

Color

White to off-white

SMILES

C[C@]([C@@]([C@H]1/C(C)=C\C(CC(C)C(O)=O)=O)(C2)C)([C@H](C1)O)C(CC[C@@]3([H])C4(C)C)=C(C2=O)[C@]3(CCC4=O)C

Structure Classification

Initial Source

Microorganisms

Ganoderma curtisii

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Reinheit & Dokumentation

Purity: 97.78%

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Data Sheet (268 KB) SDS (252 KB)

COA (251 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Yang Jiao, et al. Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3556-61. [Content Brief]