1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. 2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine

2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine 

Cat. No.: HY-152378 Purity: 96.87%
Handling Instructions Technical Support

2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

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2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine

2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine 화학구조

CAS No. : 908129-24-8

사이즈 가격 재고 수량
5 mg 해외재고보유
10 mg 해외재고보유
50 mg   견적 받기  
100 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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제품 설명

2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

분자량

247.18

화학식

C8H10FN3O5

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O[C@H]1[C@H](F)[C@H](N2C(NC(C=N2)=O)=O)O[C@@H]1CO

선적

Room temperature in continental US; may vary elsewhere.

보관

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

용액&용해도
In Vitro: 

DMSO : 125 mg/mL (505.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0456 mL 20.2282 mL 40.4563 mL
5 mM 0.8091 mL 4.0456 mL 8.0913 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.0456 mL 20.2282 mL 40.4563 mL 101.1409 mL
5 mM 0.8091 mL 4.0456 mL 8.0913 mL 20.2282 mL
10 mM 0.4046 mL 2.0228 mL 4.0456 mL 10.1141 mL
15 mM 0.2697 mL 1.3485 mL 2.6971 mL 6.7427 mL
20 mM 0.2023 mL 1.0114 mL 2.0228 mL 5.0570 mL
25 mM 0.1618 mL 0.8091 mL 1.6183 mL 4.0456 mL
30 mM 0.1349 mL 0.6743 mL 1.3485 mL 3.3714 mL
40 mM 0.1011 mL 0.5057 mL 1.0114 mL 2.5285 mL
50 mM 0.0809 mL 0.4046 mL 0.8091 mL 2.0228 mL
60 mM 0.0674 mL 0.3371 mL 0.6743 mL 1.6857 mL
80 mM 0.0506 mL 0.2529 mL 0.5057 mL 1.2643 mL
100 mM 0.0405 mL 0.2023 mL 0.4046 mL 1.0114 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine
Cat. No.:
HY-152378
수량:
MCE Japan Authorized Agent: