3-Deaza-xylouridine

Cat. No.: HY-154131: Data Sheet Handling Instructions
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3-Deaza-xylouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

3-Deaza-xylouridine 화학구조

사이즈		재고
MOQ		Minimum order quantity
50 mg		견적 받기
100 mg		견적 받기
250 mg		견적 받기
Other size		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	CC₅₀	11 μM Compound: 1	Cytostatic activity against human CEM cells after 3 days by Coulter counting analysis Cytostatic activity against human CEM cells after 3 days by Coulter counting analysis	[PMID: 19378989]
L1210	CC₅₀	1.3 μM Compound: 1	Cytostatic activity against mouse L1210 cells after 2 days by Coulter counting analysis Cytostatic activity against mouse L1210 cells after 2 days by Coulter counting analysis	[PMID: 19378989]
Vero	CC₅₀	>200 μM Compound: 4	Cytotoxicity against african green monkey Vero cells after 3 days by neutral red dye method Cytotoxicity against african green monkey Vero cells after 3 days by neutral red dye method	[PMID: 23141915]
Vero	EC₅₀	>100 μM Compound: 4	Antiviral activity against Herpes simplex virus type 1 infected in Vero cells at 0.01 ID50/cells assessed as protection against virus-induced cytopathic effect after 3 days by neutral red dye method Antiviral activity against Herpes simplex virus type 1 infected in Vero cells at 0.01 ID50/cells assessed as protection against virus-induced cytopathic effect after 3 days by neutral red dye method	[PMID: 23141915]

분자량

243.21

화학식

C₁₀H₁₃NO₆

SMILES

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C(C=C(O)C=C2)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]