3-O-Ethyl-L-ascorbic acid

製品番号: HY-W003607 純度: 99.94%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

3-O-Ethyl-L-ascorbic acid is a stable derivative of vitamin C and a cosmetic tyrosinase inhibitor. 3-O-Ethyl-L-ascorbic acid has antioxidant, anti-aging, and skin-whitening activities. 3-O-Ethyl-L-ascorbic acid is often used in the study of cosmetic.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

3-O-Ethyl-L-ascorbic acid 構造式

CAS 番号 : 86404-04-8

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	USD 27	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 27	在庫あり	Estimated Time of Arrival: December 31
Solid
1 g	$25	在庫あり	Estimated Time of Arrival: December 31
5 g	$40	在庫あり	Estimated Time of Arrival: December 31
10 g	$53	在庫あり	Estimated Time of Arrival: December 31
25 g	$84	在庫あり	Estimated Time of Arrival: December 31
50 g	$113	在庫あり	Estimated Time of Arrival: December 31
100 g	$150	在庫あり	Estimated Time of Arrival: December 31
250 g	$240	在庫あり	Estimated Time of Arrival: December 31
500 g	$319	在庫あり	Estimated Time of Arrival: December 31
> 100 g		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

Other Forms of 3-O-Ethyl-L-ascorbic acid:

3-O-Ethyl-L-ascorbic acid (Standard) お問い合わせ

おすすめ

•関連スクリーニングライブラリ:

•関連小分子:

•関連タンパク質:

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

体外実験

The cosmetic serum C-SHOT SERUM, containing 30% 3-O-Ethyl-L-ascorbic acid and 1% lactic acid, has good biocompatibility and performs excellently in photoprotection, promoting collagen synthesis, and reducing melanin content. It can prevent skin aging and pigmentation^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

204.18

分子式

C₈H₁₂O₆

CAS 番号

86404-04-8

Appearance

Solid

Color

White to off-white

SMILES

O[C@@H](CO)[C@](O1)([H])C(OCC)=C(O)C1=O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (489.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 100 mg/mL (489.77 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8977 mL	24.4884 mL	48.9769 mL
5 mM	0.9795 mL	4.8977 mL	9.7954 mL
10 mM	0.4898 mL	2.4488 mL	4.8977 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

体内:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (489.77 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 99.94%

Select Batch:

データシート (279 KB) SDS (396 KB)

COA (258 KB) HNMR (244 KB) LCMS (94 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Wayne C Liao, et al. Antioxidant Ability and Stability Studies of 3- O-Ethyl Ascorbic Acid, a Cosmetic Tyrosinase Inhibitor. J Cosmet Sci. Jul/Aug 2018;69(4):233-243. [Content Brief]

[2]. Fotis Iliopoulos, et al. 3-O-ethyl-l-ascorbic acid: Characterisation and investigation of single solvent systems for delivery to the skin. Int J Pharm X. 2019 Jul 19;1:100025. [Content Brief]

[3]. Zerbinati N, et al. The Anti-Ageing and Whitening Potential of a Cosmetic Serum Containing 3-O-ethyl-l-ascorbic Acid. Life (Basel). 2021 Apr 29;11(5):406. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	4.8977 mL	24.4884 mL	48.9769 mL	122.4422 mL
	5 mM	0.9795 mL	4.8977 mL	9.7954 mL	24.4884 mL
	10 mM	0.4898 mL	2.4488 mL	4.8977 mL	12.2442 mL
	15 mM	0.3265 mL	1.6326 mL	3.2651 mL	8.1628 mL
	20 mM	0.2449 mL	1.2244 mL	2.4488 mL	6.1221 mL
	25 mM	0.1959 mL	0.9795 mL	1.9591 mL	4.8977 mL
	30 mM	0.1633 mL	0.8163 mL	1.6326 mL	4.0814 mL
	40 mM	0.1224 mL	0.6122 mL	1.2244 mL	3.0611 mL
	50 mM	0.0980 mL	0.4898 mL	0.9795 mL	2.4488 mL
	60 mM	0.0816 mL	0.4081 mL	0.8163 mL	2.0407 mL
	80 mM	0.0612 mL	0.3061 mL	0.6122 mL	1.5305 mL
	100 mM	0.0490 mL	0.2449 mL	0.4898 mL	1.2244 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.