1. Cell Cycle/DNA Damage Anti-infection
  2. Nucleoside Antimetabolite/Analog SARS-CoV
  3. 3'OMe-m7GpppAmpG ammonium solution (100 mM)

3'OMe-m7GpppAmpG ammonium solution (100 mM)  (Synonyms: m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium solution (100 mM))

Art. -Nr.: HY-145973A Reinheit: 98.24%
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3’OMe-m7GpppAmpG (m7(3'OMeG)(5')ppp(5')(2'OMeA)pG) ammonium solution (100 mM) is a trinucleotide Cap1 analog with the structure m7 (3'OMeG)(5') ppp (5')(2'OMeA) pG, and also functions as a cis-acting ligase ribozyme inhibitor. 3’OMe-m7GpppAmpG ammonium solution (100 mM) effectively reduces free 5'-triphosphate groups on RNA transcripts, thereby enabling efficient co-transcriptional capping of in vitro transcribed mRNA. 3’OMe-m7GpppAmpG ammonium solution (100 mM) is not only widely used in the preparation of modified mRNA including trivalent influenza vaccine candidates, but also applicable to studies related to SARS-CoV-2 infection and other relevant research.

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3'OMe-m7GpppAmpG ammonium solution (100 mM)

3'OMe-m7GpppAmpG ammonium solution (100 mM) Chemische Struktur

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Solvent
1.2 mg (100 mM * 10 μL in Water) Auf Lager
Solvent
5.8 mg (100 mM * 50 μL in Water) Auf Lager
Solvent
11.6 mg (100 mM * 100 μL in Water) Auf Lager

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Beschreibung

3’OMe-m7GpppAmpG (m7(3'OMeG)(5')ppp(5')(2'OMeA)pG) ammonium solution (100 mM) is a trinucleotide Cap1 analog with the structure m7 (3'OMeG)(5') ppp (5')(2'OMeA) pG, and also functions as a cis-acting ligase ribozyme inhibitor. 3’OMe-m7GpppAmpG ammonium solution (100 mM) effectively reduces free 5'-triphosphate groups on RNA transcripts, thereby enabling efficient co-transcriptional capping of in vitro transcribed mRNA. 3’OMe-m7GpppAmpG ammonium solution (100 mM) is not only widely used in the preparation of modified mRNA including trivalent influenza vaccine candidates, but also applicable to studies related to SARS-CoV-2 infection and other relevant research[1][2][3][4].

In Vitro

3’OMe-m7GpppAmpG ammonium solution (100 mM) (4 mM; 2 h) supports the production of translationally active HA-encoding mRNA that expresses functional HA protein in HEK293 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Formel

C33H45N15O24P4.xNH3

Appearance

Liquid

Color

Colorless to light yellow

SMILES

O[C@@H]1[C@H](OC)[C@@H](COP(OP(OP(OC[C@@H]2[C@@H](OP([O-])(OC[C@@H]3[C@@H](O)[C@@H](O)[C@H](N4C(N=C(N)NC5=O)=C5N=C4)O3)=O)[C@@H](OC)[C@H](N6C(N=CN=C7N)=C7N=C6)O2)(O)=O)(O)=O)(O)=O)O[C@H]1N8C(N=C(N)NC9=O)=C9[N+](C)=C8.[x].N

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Solution, -20°C, 2 years

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Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Produktname:
3'OMe-m7GpppAmpG ammonium solution (100 mM)
Art. -Nr.:
HY-145973A
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