5α-Androstan-3β-ol (Synonyms: 3β-Hydroxy-5α-androstane)

Cat. No.: HY-W013854 Purity: 98.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
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5α-Androstan-3β-ol (Androstan), a saturated sterol, is a CAR (constitutive androstane receptor) inverse agonist ligand. 5α-Androstan-3β-ol (Androstan) increases the AmB-channel conductance in a concentration dependent manner.

For research use only. We do not sell to patients.

5α-Androstan-3β-ol Chemical Structure

CAS No. : 1224-92-6

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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Description

Molecular Weight

276.46

Formula

C₁₉H₃₂O

CAS No.

1224-92-6

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(CCC4)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 14 mg/mL (50.64 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6172 mL	18.0858 mL	36.1716 mL
5 mM	0.7234 mL	3.6172 mL	7.2343 mL
10 mM	0.3617 mL	1.8086 mL	3.6172 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98%

Select Batch:

Data Sheet (273 KB) SDS (396 KB)

COA (250 KB)

Handling Instructions (2659 KB)

References

[1]. I Tzameli, et al. T he xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR. Mol Cell Biol. 2000 May;20(9):2951-8. [Content Brief]

[2]. Olga S Ostroumova, et al. Probing amphotericin B single channel activity by membrane dipole modifiers. PLoS One. 2012;7(1):e30261. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.6172 mL	18.0858 mL	36.1716 mL	90.4290 mL
	5 mM	0.7234 mL	3.6172 mL	7.2343 mL	18.0858 mL
	10 mM	0.3617 mL	1.8086 mL	3.6172 mL	9.0429 mL
	15 mM	0.2411 mL	1.2057 mL	2.4114 mL	6.0286 mL
	20 mM	0.1809 mL	0.9043 mL	1.8086 mL	4.5214 mL
	25 mM	0.1447 mL	0.7234 mL	1.4469 mL	3.6172 mL
	30 mM	0.1206 mL	0.6029 mL	1.2057 mL	3.0143 mL
	40 mM	0.0904 mL	0.4521 mL	0.9043 mL	2.2607 mL
	50 mM	0.0723 mL	0.3617 mL	0.7234 mL	1.8086 mL

5α-Androstan-3β-ol Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5α-Androstan-3β-ol1224-92-63β-Hydroxy-5α-androstaneEndogenous MetaboliteCARAndrostanAmBInhibitorinhibitorinhibit

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5α-Androstan-3β-ol (Synonyms: 3β-Hydroxy-5α-androstane)

5α-Androstan-3β-ol Related Antibodies

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