1224-92-6
Chemical Structure
5α-Androstan-3β-ol
Synonym(s): 3β-Hydroxy-5α-androstane
- CAS No.: 1224-92-6
- Formula:C19H32O
- Molecular Weight:276.46
IUPAC Name: (3S,5S,8S,9S,10S,13S,14S)-10,13-Dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey: DJTOLSNIKJIDFF-LOVVWNRFSA-N
SMILES: C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(CCC4)C
Biological Activity: 5α-Androstan-3β-ol (Androstan), a saturated sterol, is a CAR (constitutive androstane receptor) inverse agonist ligand. 5α-Androstan-3β-ol (Androstan) increases the AmB-channel conductance in a concentration dependent manner[1][2].
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5α-Androstan-3β-ol | 98.0% | 5α-Androstan-3β-ol (Androstan), a saturated sterol, is a CAR (constitutive androstane receptor) inverse agonist ligand. 5α-Androstan-3β-ol (Androstan) increases the AmB-channel conductance in a concentration dependent manner. | ||||||||||||||||||||
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- [1]. I Tzameli, et al. T he xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR. Mol Cell Biol. 2000 May;20(9):2951-8. [Content Brief]
- [2]. Olga S Ostroumova, et al. Probing amphotericin B single channel activity by membrane dipole modifiers. PLoS One. 2012;7(1):e30261. [Content Brief]
Keywords
