5α-Androstan-3β-ol
Based on 1 Customer Validation
5α-Androstan-3β-ol (Androstan), a saturated sterol, is a CAR (constitutive androstane receptor) inverse agonist ligand. 5α-Androstan-3β-ol (Androstan) increases the AmB-channel conductance in a concentration dependent manner.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 1224-92-6
- Formula: C19H32O
- Molecular Weight:276.46
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Chemical Information
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CAS No. 1224-92-6
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Appearance Solid
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Molecular Weight 276.46
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Formula C19H32O
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Color White to off-white
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SMILES
C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(CCC4)C
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Synonyms
3β-Hydroxy-5α-androstane
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 14 mg/mL (50.64 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. I Tzameli, et al. T he xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR. Mol Cell Biol. 2000 May;20(9):2951-8. [Content Brief]
[2]. Olga S Ostroumova, et al. Probing amphotericin B single channel activity by membrane dipole modifiers. PLoS One. 2012;7(1):e30261. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6172 mL | 18.0858 mL | 36.1716 mL | 90.4290 mL |
| 5 mM | 0.7234 mL | 3.6172 mL | 7.2343 mL | 18.0858 mL | |
| 10 mM | 0.3617 mL | 1.8086 mL | 3.6172 mL | 9.0429 mL | |
| 15 mM | 0.2411 mL | 1.2057 mL | 2.4114 mL | 6.0286 mL | |
| 20 mM | 0.1809 mL | 0.9043 mL | 1.8086 mL | 4.5214 mL | |
| 25 mM | 0.1447 mL | 0.7234 mL | 1.4469 mL | 3.6172 mL | |
| 30 mM | 0.1206 mL | 0.6029 mL | 1.2057 mL | 3.0143 mL | |
| 40 mM | 0.0904 mL | 0.4521 mL | 0.9043 mL | 2.2607 mL | |
| 50 mM | 0.0723 mL | 0.3617 mL | 0.7234 mL | 1.8086 mL |
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