5′-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine

Cat. No.: HY-134554: Ficha de datos
COA

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5′-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine is an impurity in the synthesis of Capecitabine (HY-B0016).

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5′-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine Estructura química

No. CAS : 162204-30-0

Tamaño	Precio	Stock
5 mg		Pide un presupuesto y un plazo de entrega
10 mg		Pide un presupuesto y un plazo de entrega
25 mg		Pide un presupuesto y un plazo de entrega

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Descripciòn

5′-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine is an impurity in the synthesis of Capecitabine (HY-B0016)^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	0.09 mg/mL Compound: 4c	Cytotoxicity against human HeLa cells after 3 days MTT assay Cytotoxicity against human HeLa cells after 3 days MTT assay	[PMID: 22796042]
MCF7	IC₅₀	0.12 mg/mL Compound: 4c	Cytotoxicity against human MCF7 cells after 3 days MTT assay Cytotoxicity against human MCF7 cells after 3 days MTT assay	[PMID: 22796042]
NCI-H69	IC₅₀	0.37 mg/mL Compound: 4c	Cytotoxicity against human NCI-H69 cells after 3 days MTT assay Cytotoxicity against human NCI-H69 cells after 3 days MTT assay	[PMID: 22796042]

Peso molecular

359.35

Fòrmula

C₁₅H₂₂FN₃O₆

No. CAS

162204-30-0

Appearance

Solid

Color

White to off-white

SMILES

O=C1N=C(NC(OCCC(C)C)=O)C(F)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](C)O2

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvente y solubilidad

In Vitro:

Methanol : ≥ 50 mg/mL (139.14 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7828 mL	13.9140 mL	27.8280 mL
5 mM	0.5566 mL	2.7828 mL	5.5656 mL
10 mM	0.2783 mL	1.3914 mL	2.7828 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureza y Documentación

Select Batch:

Ficha de datos (272 KB) SDS (393 KB)

COA (250 KB) HNMR (179 KB) LCMS (292 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Lin Ziqi, et al. Process for preparation of Capecitabine isomer 5'-deoxy-5-fluoro-N4-(isobutoxycarbonyl)cytidine. China, CN103897006 A. 2014-07-02.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Methanol	1 mM	2.7828 mL	13.9140 mL	27.8280 mL	69.5701 mL
	5 mM	0.5566 mL	2.7828 mL	5.5656 mL	13.9140 mL
	10 mM	0.2783 mL	1.3914 mL	2.7828 mL	6.9570 mL
	15 mM	0.1855 mL	0.9276 mL	1.8552 mL	4.6380 mL
	20 mM	0.1391 mL	0.6957 mL	1.3914 mL	3.4785 mL
	25 mM	0.1113 mL	0.5566 mL	1.1131 mL	2.7828 mL
	30 mM	0.0928 mL	0.4638 mL	0.9276 mL	2.3190 mL
	40 mM	0.0696 mL	0.3479 mL	0.6957 mL	1.7393 mL
	50 mM	0.0557 mL	0.2783 mL	0.5566 mL	1.3914 mL
	60 mM	0.0464 mL	0.2319 mL	0.4638 mL	1.1595 mL
	80 mM	0.0348 mL	0.1739 mL	0.3479 mL	0.8696 mL
	100 mM	0.0278 mL	0.1391 mL	0.2783 mL	0.6957 mL