1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. iGluR
  3. 5-Iodowillardiine

5-Iodowillardiine is a potent and selective kainate receptor agonist. 5-Iodowillardiine is selective for kainate receptors composed of hGluR5 subunits.

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5-Iodowillardiine

5-Iodowillardiine Chemische Struktur

CAS. Nr. : 140187-25-3

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Beschreibung

5-Iodowillardiine is a potent and selective kainate receptor agonist. 5-Iodowillardiine is selective for kainate receptors composed of hGluR5 subunits[1].

Cellular Effect
Cell Line Type Value Description References
Oocyte EC50
33.6 3
Compound: (S)-2e
Agonist activity at cyclothiazide-desensitized rat recombinant flop iGluR1 expressed in Xenopus laevis oocytes by two electrode voltage-clamp electrophysiology method
Agonist activity at cyclothiazide-desensitized rat recombinant flop iGluR1 expressed in Xenopus laevis oocytes by two electrode voltage-clamp electrophysiology method
[PMID: 18811139]
Molekulargewicht

325.06

Formel

C7H8IN3O4

CAS. Nr.
SMILES

OC([C@@H](N)CN1C(NC(C(I)=C1)=O)=O)=O

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Molaritätsrechner

  • Verdünnungsrechner

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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5-Iodowillardiine
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