8-Hydroxy-2'-deoxyguanosine-¹³C,¹⁵N₂  (Synonyms: 8-Oxo-2-Deoxyguanosine-¹³C,¹⁵N₂)

8-Hydroxy-2'-deoxyguanosine-¹³C,¹⁵N₂ is ¹³C and ¹⁵N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis^[1].

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

286.22

C₉¹³CH₁₃N₃¹⁵N₂O₅

88847-89-6

O=C1C2=C(N=[13C]([15NH]1)[15NH2])N([C@H]3C[C@@H]([C@H](O3)CO)O)C(O)=N2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Valavanidis A, et al. 8-hydroxy-2' -deoxyguanosine (8-OHdG): A critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2009 Apr;27(2):120-39.  [Content Brief]