2. GPCR/G Protein
  3. GnRH Receptor
  4. Cetrorelix Acetate

Cetrorelix Acetate  (Synonyms: SB-75 acetate)

Cat. No.: HY-P0009A Purity: 99.98%
COA
SDS
Handling Instructions Technical Support

Cetrorelix Acetate (SB-75 acetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM.

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Custom Peptide Synthesis

Cetrorelix Acetate

Cetrorelix Acetate 화학구조

CAS No. : 145672-81-7

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

Other Forms of Cetrorelix Acetate:

Cetrorelix Acetate Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Cetrorelix Acetate

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Cetrorelix Acetate (SB-75 acetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM[1].

IC50 & Target

IC50: 1.21 nM GnRH[1].
In Vitro

Cetrorelix Acetate inhibits growth of ES-2 cell line at 1000 ng/ml. Cetrorelix Acetate has comparable antiproliferative effects as GnRH-I agonists indicating that the dichotomy of GnRH-I agonists and antagonists might not apply to the GnRH-I system in cancer cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cetrorelix Acetate Related Antibodies
분자량

1491.09

화학식

C72H96ClN17O16
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

N-acetyl-{2-Naph-Ala}-{Cl-Phe}-{3Py-Ala}-Ser-Tyr-{Cit}-Leu-Arg-Pro-Ala-NH2
Sequence Shortening

Ac-{2-Naph-Ala}-{Cl-Phe}-{3Py-Ala}-SY-{Cit}-LRPA-NH2
선적

Room temperature in continental US; may vary elsewhere.
보관

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

용액&용해도
In Vitro: 

DMSO : 50 mg/mL (33.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 2 mg/mL (1.34 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6707 mL 3.3533 mL 6.7065 mL
5 mM 0.1341 mL 0.6707 mL 1.3413 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서

Purity: 99.98%

SDS (419 KB)

COA (250 KB) RP-HPLC (262 KB) MS (71 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 0.6707 mL 3.3533 mL 6.7065 mL 16.7663 mL
DMSO 5 mM 0.1341 mL 0.6707 mL 1.3413 mL 3.3533 mL
10 mM 0.0671 mL 0.3353 mL 0.6707 mL 1.6766 mL
15 mM 0.0447 mL 0.2236 mL 0.4471 mL 1.1178 mL
20 mM 0.0335 mL 0.1677 mL 0.3353 mL 0.8383 mL
25 mM 0.0268 mL 0.1341 mL 0.2683 mL 0.6707 mL
30 mM 0.0224 mL 0.1118 mL 0.2236 mL 0.5589 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Cetrorelix Acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cetrorelix145672-81-7SB-75SB75SB 75GnRH ReceptorGonadotropin releasing hormone receptorGNRHRInhibitorinhibitorinhibit

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Inquiry Information

상품명:
Cetrorelix Acetate
Cat. No.:
HY-P0009A
수량:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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