1. Natural Products
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  3. Moraceae
  4. Humulus lupulus L.

Humulus lupulus L.

Synonyms: hops

Humulus lupulus L. (18):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1067
    Xanthohumol 6754-58-1 99.97%
    Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
  • HY-N2584
    (2S)-Isoxanthohumol 70872-29-6 99.77%
    (2S)-Isoxanthohumol is a microbial biotransformed metabolite of the hop prenylflavanone Isoxanthohumol.
  • HY-N1066
    Xanthohumol D 274675-25-1 99.21%
    Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro.
    Xanthohumol D
  • HY-107198
    (2S)-6-Prenylnaringenin 68236-13-5 99.78%
    (2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface.
  • HY-N2584A
    Isoxanthohumol 521-48-2 99.90%
    Isoxanthohumol is a prenylflavonoid from hops and beer. Isoxanthohumol exhibits an antiproliferative activity against several human cancer cell lines. Isoxanthohumol inhibits the development of lung metastatic foci in tumor-challenged animals. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).
  • HY-N10867
    β-Acids colupulone 468-27-9
    β-Acids colupulone is the bitter substance. β-Acids colupulone can be isolated from hops.
    β-Acids colupulone
  • HY-122375
    Palustrol 5986-49-2
    Palustrol is a natural sesquiterpenoid compound.
  • HY-N11769
    Xanthohumol C 189299-05-6
    Xanthohumol C is a prenylchalcone, that can be isolated from the hops of Humulus lupulus.
    Xanthohumol C
  • HY-N2787
    8-​Prenylnaringenin 53846-50-7 99.30%
    8-prenylnaringenin is a prenylflavonoid isolated from hop cones Humulus lupulus, with cytotoxicity. 8-prenylnaringenin has anti-proliferative activity against HCT-116 colon cancer cells via induction of intrinsic and extrinsic pathway-mediated apoptosis. 8-Prenylnaringenin also promotes recovery from immobilization-induced disuse muscle atrophy through activation of the Akt phosphorylation pathway in mice .
  • HY-122966
    Desmethylxanthohumol 115063-39-3 99.66%
    Desmethylxanthohumol is a prenylated hydroxychalcone isolated from hop cones (Humulus lupulus L.). Desmethylxanthohumol is a powerful apoptosis inducing agent. Desmethylxanthohumol has antiplasmodial, antiproliferative, and antioxidant bioactivities.
  • HY-124923
    Lupulone 468-28-0
    Lupulone is a beta-acid from the hop plant H. lupulus with diverse biological activities including antibacterial, antioxidant, and anticarcinogenic properties.
  • HY-N10668
    2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid 57061-17-3
    2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid (compound 29) is a natural polyphenol compound found in hop bract.
    2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid
  • HY-N6084
    Humulone 26472-41-3 99.33%
    Humulone (α-Lupulic acid), a prenylated phloroglucinol derivative, is a potent cyclooxygenase-2 (COX-2) inhibitor. Humulone acts as a positive modulator of GABAA receptor at low micromolar concentrations. Humulone is an inhibitor of bone resorption. Humulone possesses antioxidant, anti-angiogenic and apoptosis-inducing properties.
  • HY-N9140
    Hulupinic acid 1891-42-5
    Hulupinic acid is a prominent oxidation product of hop acids.
    Hulupinic acid
  • HY-N9969
    Lupulone C 613683-50-4
    Lupulone C (Compound 9) is an inhibitor of NO production.
    Lupulone C
  • HY-122416
    6,8-Diprenylnaringenin 68236-11-3
    6,8-Diprenylnaringenin (Lonchocarpol A; Senegalensin), a hop prenylflavonoid, is a inhibitor of breast cancer resistance protein (BCRP/ABCG2). 6,8-Diprenylnaringenin inhibits ABCG2-mediated efflux of Mitoxantrone, and 3H-Methotrexate transport (IC50=0.41 μM) in HEK293 cells. 6,8-Diprenylnaringenin exhibits some estrogenicity, but its potency is less than 1% of that of 8-Prenylnaringenin.
  • HY-N11055
    7-O-Methyl-6-Prenylnaringenin 261776-61-8
    7-O-Methyl-6-Prenylnaringenin is an active compound. 7-O-Methyl-6-Prenylnaringenin can be isolated from Humulus lupulus.
  • HY-N10917
    Xanthohumol I 688360-06-7
    Xanthohumol I, a chalkone, is a derivative of Xanthohumol (HY-N1067). Xanthohumol is a Cholinesterase (ChE) inhibitor, which inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) wih IC50s of 71.34 μM and 32.67 μM, respectively. The hydroxy compound of Xanthohumol (3-hydroxy-xanthohumol), also shoes inhibitory effect on AChE and BChE with IC50s of 51.25 μM and 63.07 μM.
    Xanthohumol I