2. Natural Products
  3. Plants
  4. Moraceae
  5. Humulus lupulus L.

Humulus lupulus L.

Synonyms: hops

Humulus lupulus L. (32):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1067
    Xanthohumol 6754-58-1 99.94%
    Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
    Xanthohumol
  • HY-N2584A
    Isoxanthohumol 521-48-2 99.91%
    Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases.
    Isoxanthohumol
  • HY-N6084
    Humulone 26472-41-3 99.46%
    Humulone (α-Lupulic acid), a prenylated phloroglucinol derivative, is a potent cyclooxygenase-2 (COX-2) inhibitor. Humulone acts as a positive modulator of GABAA receptor at low micromolar concentrations. Humulone is an inhibitor of bone resorption. Humulone possesses antioxidant, anti-angiogenic and apoptosis-inducing properties.
    Humulone
  • HY-107198
    (2S)-6-Prenylnaringenin 68236-13-5 99.84%
    (2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface.
    (2S)-6-Prenylnaringenin
  • HY-N2787
    8-​Prenylnaringenin 53846-50-7 99.63%
    8-Prenylnaringenin is an orally active prenyl flavonoid. 8-Prenylnaringenin can be isolated from the hop spike Humulus lupulus. 8-Prenylnaringenin activates the PI3K/Akt pathway and the AMPK pathway, upregulates OXPHOS complexes (II, III, and V) and Sirt1, and reduces ROS production and SOD activity. 8-Prenylnaringenin improves muscle atrophy and obesity and inhibits angiogenesis. 8-Prenylnaringenin exhibits anticancer activity against glioblastoma and colon cancer. 8-Prenylnaringenin also has LH/FSH regulatory activity. 8-prenylnaringenin may be used in bone health research.
    8-​Prenylnaringenin
  • HY-W750903
    Dihydroxanthohumol 102448-00-0
    Dihydroxanthohumol is a chalcone found in Humulus lupulus L. Dihydroxanthohumol is a nitric oxide (NO) production inhibitor. Dihydroxanthohumol slightly suppresses LPS (HY-D1056)/IFN-γ-induced iNOS protein expression and NO production. Dihydroxanthohumol exhibits cytotoxicity at high concentrations.
    Dihydroxanthohumol
  • HY-N18095
    Tricyclodehydroisohumulone 56143-68-1
    Tricyclodehydroisohumulone (Compound 10) is an oxidation product of α-acid, which is found in hop resin.
    Tricyclodehydroisohumulone
  • HY-N18262
    Humulinone 981-03-3
    Humulinone is a foam-enhancing agent. Humulinone interacts with Protein Z, with a binding constant of 1.64 × 105 M-1. Humulinone improves the foamability, foam stability and foam texture of Protein Z. Humulinone can be used in beer research.
    Humulinone
  • HY-34409
    3-Methyl-2-butenal 107-86-8
    3-Methyl-2-butenal (3-Methylbut-2-en-1-al) is an enone aldehyde that occurs in hops (Humulus lupulus L.).
    3-Methyl-2-butenal
  • HY-126109
    (±)-8-Prenylnaringenin 68682-02-0 99.97%
    (±)-8-Prenylnaringenin, a natural prenylated flavonoid, is a potent phytoestrogen. (±)-8-Prenylnaringenin is an orally active selective estrogen receptor modulator (SERM) (Estrogen Receptor/ERR) that inhibits ERα and ERβ with IC50s of 57 nM and 68 nM, respectively. (±)-8-Prenylnaringenin has anticancer effects, and can be used for osteoporosis research.
    (±)-8-Prenylnaringenin
  • HY-N2584
    (2S)-Isoxanthohumol 70872-29-6 99.42%
    (2S)-Isoxanthohumol is a microbial biotransformed metabolite of the hop prenylflavanone Isoxanthohumol.
    (2S)-Isoxanthohumol
  • HY-124923
    Lupulone 468-28-0 99.0%
    Lupulone is a beta-acid from the hop plant H. lupulus with diverse biological activities including antibacterial, antioxidant, and anticarcinogenic properties.
    Lupulone
  • HY-122966
    Desmethylxanthohumol 115063-39-3
    Desmethylxanthohumol is a prenylated hydroxychalcone isolated from hop cones (Humulus lupulus L.). Desmethylxanthohumol is a powerful apoptosis inducing agent. Desmethylxanthohumol has antiplasmodial, antiproliferative, and antioxidant bioactivities.
    Desmethylxanthohumol
  • HY-N11769
    Xanthohumol C 189299-05-6 99.20%
    Xanthohumol C is a prenylchalcone, that can be isolated from the hops of Humulus lupulus.
    Xanthohumol C
  • HY-N10668
    2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid 57061-17-3 99.60%
    2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid (compound 29) is a natural polyphenol compound found in hop bract.
    2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid
  • HY-N1066
    Xanthohumol D 274675-25-1 99.21%
    Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro.
    Xanthohumol D
  • HY-N1067R
    Xanthohumol (Standard) 6754-58-1
    Xanthohumol (Standard) is the analytical standard of Xanthohumol. This product is intended for research and analytical applications. Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
    Xanthohumol (Standard)
  • HY-W010203
    2-Decanone 693-54-9
    2-Decanone is an antifungal agent. 2-Decanone inhibits pathogen mycelial growth, spore germination, and appressorium formation. 2-Decanone downregulates spore germination-related genes (MfBmp1) and penetration structure formation genes (MfPls1), inducing reactive oxygen species (ROS) accumulation to trigger mitochondrial damage and subsequent spore apoptosis. 2-Decanone is promising for research of postharvest disease control in fruits and vegetables.
    2-Decanone
  • HY-N11238
    (-)-α-Cadinene 24406-05-1
    (-)-α-Cadinene is a sesquiterpene hydrocarbon that can be isolated from Japanese hops. (-)-α-Cadinene is a natural product.
    (-)-α-Cadinene
  • HY-W1121873
    β-Caryophyllene alcohol 472-97-9
    β-Caryophyllene alcohol is an active metabolite of β-caryophyllene (HY-N1415) with potent anti-asthma and anti-inflammation activity. β-Caryophyllene alcohol shows significant anti-asthmatic effect in guinea pigs. β-Caryophyllene alcohol can be used for asthma and inflammation research.
    β-Caryophyllene alcohol