2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. Neurokinin B

Neurokinin B belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect.

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Neurokinin B

Neurokinin B 構造式

CAS 番号 : 86933-75-7

容量 価格（税別） 在庫状況 数量
1 mg $108 在庫あり
5 mg $270 在庫あり
10 mg $405 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Other Forms of Neurokinin B:

Neurokinin B 関連抗体

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Neurokinin Receptor アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
NK1R NK2R NK3R

  • 生物活性

  • 純度とドキュメンテーション

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製品説明

Neurokinin B belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect[1].

IC50 & Target

Neurokinin receptor[1]
体外実験

Neurokinin B (NKB) belongs to the tachykinin family of peptides that initially included the neuropeptides substance P (SP), neurokinin A (NKA), and NKB and more recently, endokinins and hemokinins. Tachykinins bind a family of G-protein-coupled receptors (GPCRs)-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Neurokinin B 関連抗体
分子量

1210.42

分子式

C55H79N13O14S2
CAS 番号
Appearance

Solid

Color

White to off-white

Sequence

Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2
Sequence Shortening

DMHDFFVGLM-NH2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Sealed storage, away from moisture
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

H2O : 20 mg/mL (16.52 mM; ultrasonic and adjust pH to 9 with NH3·H2O)

DMSO : 5 mg/mL (4.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8262 mL 4.1308 mL 8.2616 mL
5 mM 0.1652 mL 0.8262 mL 1.6523 mL
10 mM 0.0826 mL 0.4131 mL 0.8262 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 98.48%

COA (241 KB) RP-HPLC (363 KB) MS (102 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 0.8262 mL 4.1308 mL 8.2616 mL 20.6540 mL
H2O 5 mM 0.1652 mL 0.8262 mL 1.6523 mL 4.1308 mL
10 mM 0.0826 mL 0.4131 mL 0.8262 mL 2.0654 mL
15 mM 0.0551 mL 0.2754 mL 0.5508 mL 1.3769 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Neurokinin B Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Neurokinin B86933-75-7Neurokinin ReceptorNK receptorTachykinin receptorInhibitorinhibitorinhibit

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製品名:
Neurokinin B
製品番号:
HY-P0242
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