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Nystatin

57 Cited Publications
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Based on 57 publication(s) in Google Scholar

Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion. Nystatin is a cholesterol-sequestering agent, partially prevents Oxaliplatin-induced lipid raft aggregation, DR4 and DR5 clustering, and thereby reduces apoptosis.

For research use only. We do not sell to patients.

  • Purity: 99.64%
  • CAS No.: 1400-61-9
  • Formula: C47H75NO17
  • Molecular Weight:926.09
  • Storage:

    -20°C, sealed storage, away from moisture and light

    * The compound is unstable in solutions, freshly prepared is recommended.

  • Nystatin Chemical Structure
    Nystatin Chemical Structure
  • Experimental Validation Results for Nystatin
  • Experimental Validation Results for Nystatin
  • Experimental Validation Results for Nystatin
  • Experimental Validation Results for Nystatin
  • Experimental Validation Results for Nystatin
CAS No.: 1400-61-9
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  • Nystatin Chemical Structure
    Nystatin Chemical Structure
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    Nystatin purchased from MedChemExpress. Usage Cited in: J Am Chem Soc. 2025 Oct 29;147(43):39912-39925. [Abstract]

    Customer Validation
     Cytotoxicity of 0.8 nM DDCs on A431 cells in the presence of 50 nM BafA, 50 nM MG132, and 1 μM Nystatin, respectively. Cells treated with inhibitors alone showed no cytotoxicity at the concentrations used in DDC treatments. Dead cells were labeled by 1 μg/mL propidium iodide after 48 h of treatment.

  • 1/16

    Nystatin purchased from MedChemExpress. Usage Cited in: Nat Nanotechnol. 2025 Feb;20(2):296-302. [Abstract]

    Customer Validation
     EGFR degradation in MDA-MB-231 cells after incubation with 500 nM NTZ-NPs and 5 μM Nystatin for 24 h.

  • 1/16

    Nystatin purchased from MedChemExpress. Usage Cited in: Biomaterials. 2022 Feb:281:121373. [Abstract]

    Customer Validation
     Flow cytometry quantitation of cellular uptake of NR-EA-PLN(C/S) by analyzing NR fluorescence intensity for various incubation conditions. Caco-2 cells were cultured in the flask and incubated at 4 °C or 37 °C with endocytosis inhibitors (EIPA, Cytochalasin-D, Nystatin (11 μM) and Chlorpromazine) for 2 h. The NR concentration was 3.57 μg/mL.

  • 1/16

    Nystatin purchased from MedChemExpress. Usage Cited in: Adv Funct Mater. 2020, 2004940.

    Customer Validation
     Endocytosis analysis of MUSE with endocytosis inhibitors (chloroquine, chloropromazine, Nystatin (50 µg/mL; 1 h), wortmannin) by FCM and CLSM.

  • 1/16

    Nystatin purchased from MedChemExpress. Usage Cited in: J Am Chem Soc. 2018 Dec 12;140(49):17234-17240. [Abstract]

    Customer Validation
     Cells were pretreated for 0.5 h with the indicated inhibitor (e.g., Nystatin, 25 μg/mL) to 2 h treatment with 2 μM K4-GFP in the continued presence of inhibitor, washed, and analyzed by flow cytometry. Treatment at 4 °C instead of 37 °C was included as a control (blue bars).

  • Nystatin