2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Nombre del producto No. CAS Pureza Estructura química
  • HY-153722A
    Dodicin hydrochloride 36895-38-2 98%
    Dodicin hydrochloride is an effective disinfectant with broad antimicrobial activity.
    Dodicin hydrochloride
  • HY-153837A
    ISIS 14803 sodium
    ISIS 14803 sodium is a 20-unit antisense phosphorothioate oligodeoxynucleotide that binds to hepatitis C virus (HCV) RNA at the translation initiation region of the internal ribosome entry site (IRES) and inhibits protein expression in cell culture.
    ISIS 14803 sodium
  • HY-153837C
    ISIS 14803 sodium scrambled negative control 98%
    ISIS 14803 sodium scrambled negative control is the sequence scrambled negative control of ISIS 14803 sodium.
    ISIS 14803 sodium scrambled negative control
  • HY-153837D
    FAM labled ISIS 14803 sodium 98%
    FAM labled ISIS 14803 sodiumis a FAM labled ISIS 14803 sodium.
    FAM labled ISIS 14803 sodium
  • HY-153837E
    Cy3 labled ISIS 14803 sodium 98%
    Cy3 labled ISIS 14803 sodium is a Cy3 labled ISIS 14803 sodium.
    Cy3 labled ISIS 14803 sodium
  • HY-15407BR
    Sacubitril sodium (Standard) 149690-05-1 98%
    Sacubitril (sodium) (Standard) is the analytical standard of Sacubitril (sodium). This product is intended for research and analytical applications. Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19.
    Sacubitril sodium (Standard)
  • HY-15407S3
    Sacubitril-13C4 98%
    Sacubitril-13C4 (AHU-377-13C4) is a 13C-labeled version of Sacubitril (HY-15407). Sacubitril is an orally active inhibitor of neprilysin NEP (IC50=5 nM). Sacubitril is used in research on heart failure, hypertension and COVID-19.
    Sacubitril-13C4
  • HY-15592AS
    Cabotegravir-d3 sodium 98%
    Cabotegravir-d3 (sodium) is the deuterium labeled Cabotegravir sodium. Cabotegravir sodium is a highly potent HIV integrase inhibitor with an IC50 value of 2.5 nM for HIVADA. Cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltr
    Cabotegravir-d3 sodium
  • HY-15592S2
    Cabotegravir-d3-1 98%
    Cabotegravir d3-1 (GSK-1265744-d3-1) is a deuterium substitute of Cabotegravir. Cabotegravir is a potent HIV integrase inhibitor used in AIDS research
    Cabotegravir-d3-1
  • HY-15592S4
    Cabotegravir-d6
    Cabotegravir-d6 (GSK-1265744-d6) is the deuterium labeled Cabotegravir (HY-15592). Cabotegravir (GSK-1265744) is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIVADA, OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS.
    Cabotegravir-d6
  • HY-15602AS
    Ledipasvir-d6 hydrochloride 98%
    Ledipasvir-d6 hydrochloride is deuterated labeled Ledipasvir acetone (HY-15602A). Ledipasvir acetone (GS-5885 acetone) is the active ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.
    Ledipasvir-d6 hydrochloride
  • HY-156063A
    (2R,4R)-UCB7362 hydrochloride 2610631-18-8 98%
    (2R,4R)-UCB7362 hydrochloride is the (2R,4R) isomer of UCB7362 (HY-151568). (2R,4R)-UCB7362 hydrochloride is an inhibitor of plasma proteinase X (PMX) with antimalarial activity.
    (2R,4R)-UCB7362 hydrochloride
  • HY-156703S
    HBV-IN-39-d3 2173356-23-3 98%
    HBV-IN-39-d3 (Example 14) is a deuterated HBV-IN-39 (Example 13). HBV-IN-39 is an HBV inhibitor. HBV-IN-39-d3 has better oral bioavailability than HBV-IN-39.
    HBV-IN-39-d3
  • HY-15971AR
    AMD 3465 (Standard) 185991-24-6
    AMD 3465 (Standard) is the analytical standard of AMD 3465. This product is intended for research and analytical applications. AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM), but has no effect on CCR5-using (R5) viruses.
    AMD 3465 (Standard)
  • HY-159796A
    Cefetecol 117211-03-7
    Ceftezole (GR69153) is a broad-spectrum cephalosporin antibiotic and an α-glucosidase inhibitor. Ceftezole inhibits bacterial cell lysis by inhibiting cell wall synthesis and binding to penicillin-binding proteins (PBPs). Ceftezole exhibits in vivo anti-diabetic activity in diabetic mice. Ceftezole can be used in antibacterial and anti-diabetic research.
    Cefetecol
  • HY-160255A
    N-Cbz-D-Cysteine 156916-81-3 98%
    N-Cbz-D-Cysteine (Cbz-D-Cys) (compound 5) is a potent β-lactamase II inhibitor with a Ki value of 20.1 µM.
    N-Cbz-D-Cysteine
  • HY-161239A
    IB-96212 220858-11-7 98%
    IB-96212 (compound 5) is a member of oligomycin class which can be extracted ftom the marine Micromonospora sp. L-25-ES25-008 ref. IB-96212 is an antitumor antibiotic against P-388, it also exhibits antimicrobial activity against Micrococcus luteus.
    IB-96212
  • HY-162595A
    BDM88855 hydrochloride 2892824-26-7 98%
    BDM88855 hydrochloride is an allosteric inhibitor for the homolog AcrB protein. BDM88855 hydrochloride can boost the antibacterial effect of a panel of antibiotics (eg: Oxacillin (HY-B0925A), Linezolid (HY-10394), Novobiocin (HY-B0425), etc.) on wild-type E. coli.
    BDM88855 hydrochloride
  • HY-162782A
    V–C6–Bg-PhCl TFA 98%
    V–C6–Bg-PhCl TFA (compound 5e) is a biguanide-vancomycin conjugate. V–C6–Bg-PhCl TFA has broad-spectrum antibacterial activity against both Gram-negative and Gram-positive bacteria.
    V–C6–Bg-PhCl TFA
  • HY-16305S2
    Maribavir-d7
    Maribavir-d7 (1263W94-d7) is the deuterium labeled Maribavir (HY-16305). Maribavir is a potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro, with an IC50 of 3 nM. Maribavir has potent antiviral activity against HCMV and Epstein-Barr virus (EBV).
    Maribavir-d7
Cat. No. Nombre del producto / Synonyms Application Reactivity