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Cat. No.: HY-162782A

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V–C6–Bg-PhCl TFA

V–C6–Bg-PhCl TFA (compound 5e) is a biguanide-vancomycin conjugate. V–C6–Bg-PhCl TFA has broad-spectrum antibacterial activity against both Gram-negative and Gram-positive bacteria.

For research use only. We do not sell to patients.

Formula: C₈₂H₉₇Cl₃F₃N₁₅O₂₅
Molecular Weight:1856.09

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

V–C6–Bg-PhCl TFA Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

V–C6–Bg-PhCl TFA (compound 5e) is a biguanide-vancomycin conjugate. V–C6–Bg-PhCl TFA has broad-spectrum antibacterial activity against both Gram-negative and Gram-positive bacteria^[1].

All Antibiotic Isoforms :

Chemical Information

Molecular Weight 1856.09
Formula C₈₂H₉₇Cl₃F₃N₁₅O₂₅
SMILES

C[C@]1(N)C[C@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2OC3=C(OC4=CC=C([C@H]([C@H](C(N[C@H]5CC(N)=O)=O)NC([C@@H](CC(C)C)NC)=O)O)C=C4Cl)C=C([C@H](C(N[C@@H]6C7=CC8=C(O)C=C7)=O)NC5=O)C=C3OC9=C(Cl)C=C([C@H]([C@@H](C(N[C@H](C(NCCCCCCNC(/N=C(N)/NC%10=CC=C(Cl)C=C%10)=N)=O)C%11=CC(O)=CC(O)=C8%11)=O)NC6=O)O)C=C9)O[C@@H](C)[C@H]1O.O=C(C(F)(F)F)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Rahn HP, et al. Biguanide-Vancomycin Conjugates are Effective Broad-Spectrum Antibiotics against Actively Growing and Biofilm-Associated Gram-Positive and Gram-Negative ESKAPE Pathogens and Mycobacteria. J Am Chem Soc. 2024 Aug 14;146(32):22541-22552. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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