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Cat. No.: HY-156063A

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(2R,4R)-UCB7362 hydrochloride

Name: (2R,4R)-UCB7362 hydrochloride
Brand: MedChemExpress
SKU: HY-156063A
Price: 358.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(2R,4R)-UCB7362 hydrochloride is the (2R,4R) isomer of UCB7362 (HY-151568). (2R,4R)-UCB7362 hydrochloride is an inhibitor of plasma proteinase X (PMX) with antimalarial activity.

For research use only. We do not sell to patients.

CAS No.: 2610631-18-8
Formula: C₂₅H₂₆ClN₅O₃.xHCl
Molecular Weight:479.96(free base)

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

(2R,4R)-UCB7362 hydrochloride Chemical Structure

CAS No.: 2610631-18-8

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Description

(2R,4R)-UCB7362 hydrochloride is the (2R,4R) isomer of UCB7362 (HY-151568). (2R,4R)-UCB7362 hydrochloride is an inhibitor of plasma proteinase X (PMX) with antimalarial activity^[1].

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Chemical Information

CAS No. 2610631-18-8
Molecular Weight 479.96(free base)
Formula C₂₅H₂₆ClN₅O₃.xHCl
SMILES

O=C(NC1=CC=CC([C@@](CC(N2[C@H]3C[C@@H](C)OCC3)=O)(C)NC2=N)=C1Cl)C4=CC=CC(C#N)=C4.Cl.[x]
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lowe MA, et al. Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362. J Med Chem. 2022 Oct 27;65(20):14121-14143. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(2R,4R)-UCB7362 hydrochloride

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