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Cat. No.: HY-156063

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(2R,4R)-UCB7362

(2R,4R)-UCB7362 is the (2R,4R) isomer of UCB7362 (HY-151568). UCB7362 is an inhibitor of plasma proteinase X (PMX) with antimalarial activity.

For research use only. We do not sell to patients.

CAS No.: 2610631-17-7
Formula: C₂₅H₂₆ClN₅O₃
Molecular Weight:479.96

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

(2R,4R)-UCB7362 Chemical Structure

CAS No.: 2610631-17-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

(2R,4R)-UCB7362 is the (2R,4R) isomer of UCB7362 (HY-151568). UCB7362 is an inhibitor of plasma proteinase X (PMX) with antimalarial activity^[1].

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Chemical Information

CAS No. 2610631-17-7
Molecular Weight 479.96
Formula C₂₅H₂₆ClN₅O₃
SMILES

C[C@@]1(C2=C(C(NC(C3=CC(C#N)=CC=C3)=O)=CC=C2)Cl)CC(N([C@H]4C[C@H](OCC4)C)C(N)=N1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lowe MA, et al. Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362. J Med Chem. 2022 Oct 10. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(2R,4R)-UCB7362

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(2R,4R)-UCB7362 Related Classifications

HY-156063 Related Classifications