2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-16973S
    Fluralaner-13C2,15N,d3 98.35%
    Fluralaner-13C2,15N,d3 is the deuterium, 13C-, and 15-labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
    Fluralaner-13C2,15N,d3
  • HY-169790
    Phomarin 6866-87-1 98.53%
    Phomarin is an inhibitor for dihydrofolate reductase (DHFR). Phomarin exhibits activity against Plasmodium parasites and fungi including Mycrobotryum violaceum and Botrytis cinerea. Phomarin can be used for the research of malaria and fungal infections.
    Phomarin
  • HY-169972
    Succinate dehydrogenase-IN-5 3106182-23-1 98.26%
    Succinate dehydrogenase-IN-5 (Compound M8) is the inhibitor for succinate dehydrogenase. Succinate dehydrogenase-IN-5 interfers with the energy metabolism and growth of fungi, inhibits Rhizoctonia solani, Sclerotinia sclerotiorum, Botrytis cinerea and Fusarium graminearum with EC50 < 0.3 μg/mL.
    Succinate dehydrogenase-IN-5
  • HY-170472
    Bpin-Bedaquiline 2375174-10-8
    Bpin-Bedaquiline (compound 2) is a boronic ester precursor of Bedaquiline (HY-14881). Bpin-Bedaquiline can react with H476Br to synthesize 76Br-Bedaquiline.
    Bpin-Bedaquiline
  • HY-171615
    (4-Phenylphenoxy)phosphonic acid 46817-52-1 99.70%
    (4-Phenylphenoxy) phosphonic acid is a protein tyrosine phosphatase (PTP) inhibitor (KM: 86 μM). (4-Phenylphenoxy) phosphonic acid can be used in tuberculosis research.
    (4-Phenylphenoxy)phosphonic acid
  • HY-17392R
    Zalcitabine (Standard) 7481-89-2 98.56%
    Zalcitabine (Standard) is the analytical standard of Zalcitabine. This product is intended for research and analytical applications. Zalcitabine is a potent nucleoside analogue reverse transcriptase inhibitor used in the treatment of HIV infection.
    Zalcitabine (Standard)
  • HY-174134
    PI4Kβ/PKG-IN-2 3099010-20-2 99.34%
    PI4Kβ/PKG-IN-2 (Compound 20) is an orally active dual inhibitor of Plasmodium phosphatidylinositol 4-kinase beta (PI4Kβ) and cGMP-dependent protein kinase (PKG). PI4Kβ/PKG-IN-2 has potent inhibitory effects on Plasmodium. PI4Kβ/PKG-IN-2 is promising for research of malaria.
    PI4Kβ/PKG-IN-2
  • HY-17413R
    Zidovudine (Standard) 30516-87-1 99.84%
    Zidovudine (Standard) is the analytical standard of Zidovudine. This product is intended for research and analytical applications. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.
    Zidovudine (Standard)
  • HY-17424R
    Penciclovir (Standard) 39809-25-1 99.44%
    Penciclovir (Standard) is the analytical standard of Penciclovir. This product is intended for research and analytical applications. Penciclovir (VSA 671) is a potent and selective anti-herpesvirus agent with EC50 values of 0.5, 0.8 µg/ml for HSV-1 (HFEM), HSV-2 (MS), respectively. Penciclovir shows anti-herpesvirus activity with no-toxic. Penciclovir preventes mortality in mouse.
    Penciclovir (Standard)
  • HY-17595R
    Mebendazole (Standard) 31431-39-7 99.49%
    Mebendazole (Standard) is the analytical standard of Mebendazole. This product is intended for research and analytical applications. Mebendazole is a highly effective, broad-spectrum antihelmintic against nematode infestations. Mebendazole also exhibits inhibitory effect against glioblastoma multiforme (GBM), inhibits Hedgehog pathway and tubulin polymerization. Mebendazole is orally active and can cross CNS penetration.
    Mebendazole (Standard)
  • HY-176969
    Antimicrobial agent-44 2009354-38-3 99.86%
    Antimicrobial agent-44 (Compound 7C) is an antibacterial agent.
    Antimicrobial agent-44
  • HY-176970
    Antimicrobial agent-45 2043299-21-2 99.59%
    Antimicrobial agent-45 (Compound 16) is a broad-spectrum antibacterial agent. Antimicrobial agent-45 exhibits MICs against Cr. neoformans, S. aureus, MRSA and My. intracellulare of 9.25, 74.04, 74.04 and 74.04 μM respectively. Antimicrobial agent-45 can be used for the study of cryptococcal infections.
    Antimicrobial agent-45
  • HY-177116
    GPR15 antagonist-1 252280-67-4 99.70%
    GPR15 antagonist-1 (Compound 5) is a GPR15 antagonist. G protein-coupled receptor 15 (GPR15) is an extensively studied GPCRs involving HIV infection, colonic inflammation, and smoking-related diseases.
    GPR15 antagonist-1
  • HY-177979
    DNA-GAG 54230-76-1
    DNA-GAG is a slow substrate for Ricin toxin A-chain (RTA). RTA depurinates a single adenylate on a GAGA stem-loop region of eukaryotic 28S RNA, making it a potent toxin.
    DNA-GAG
  • HY-179690
    Antiparasitic agent-30 671754-20-4 98%
    Antiparasitic agent-30 is a potent adenosine kinase TbrAK modulator and antitrypanosomal agent. Antiparasitic agent-30 exhibits significant inhibitory activity against Trypanosoma brucei rhodesiense, while enhancing the activity of recombinant TbrAK(EC50=38 nM, Ka=75 nM-497 nM). Antiparasitic agent-30 exerts its pharmacological effects by eliminating intrinsic substrate inhibition and hyperactivating TbrAK in Trypanosoma brucei rhodesiense. Antiparasitic agent-30 serves as a valuable tool molecule for studying acute African human trypanosomiasis (sleeping sickness).
    Antiparasitic agent-30
  • HY-179691
    Antiviral agent 75 314035-79-5
    Antiviral agent 75 (example D26) is a Ebolavirus (EBOV) and Bundibugyo ebolavirus (BDBV) inhibitor with IC50s of 0.11 μM and 0.75 μM, respectively. Antiviral agent 75 can be used for the study of filovirus infection.
    Antiviral agent 75
  • HY-185307
    Anti-Influenza agent 11 3118478-63-7 99.75%
    Anti-Influenza agent 11 (compound L08) is an inhibitor of Influenza Virus and can be used in the research of influenza virus infection.
    Anti-Influenza agent 11
  • HY-B0136R
    Cefdinir (Standard) 91832-40-5 98%
    Cefdinir (Standard) is the analytical standard of Cefdinir. This product is intended for research and analytical applications. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin.
    Cefdinir (Standard)
  • HY-B0276R
    Ethionamide (Standard) 536-33-4 99.91%
    Ethionamide (Standard) is the analytical standard of Ethionamide. This product is intended for research and analytical applications. Ethionamide (2-ethylthioisonicotinamide) is a second-line anti-tuberculosis antibiotic.
    Ethionamide (Standard)
  • HY-B0334R
    Sulbactam (Standard) 68373-14-8 99.66%
    Sulbactam (Standard) is the analytical standard of Sulbactam. This product is intended for research and analytical applications. Sulbactam (CP45899) is a competitive, irreversible beta-lactamase inhibitor. Sulbactam shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex.
    Sulbactam (Standard)
Cat. No. Product Name / Synonyms Application Reactivity