2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N6846
    10-​Isobutyryloxy-​8,​9-​epoxythymol isobutyrate 22518-06-5 98%
    10-Isobutyryloxy-8,9-epoxythymol isobutyrate is a major constituent of Inula helenium and Inula royleana root cultures. 10-Isobutyryloxy-8,9-epoxythymol isobutyrate shows moderate antimicrobial activity against Staphylococcus aureus FDA 209 P, Staphylococcus aureus, Enterococcus faecalis, Candida albicans and Pseudomonas aeruginosa with MICs of 50, 250, 250, 250, and 1000 μg/mL, respectively.
    10-​Isobutyryloxy-​8,​9-​epoxythymol isobutyrate
  • HY-N6848
    Acetylseneciphylline N-oxide 123844-00-8 98%
    Acetylseneciphylline N-oxide is a pyrrolizine alkaloid that is seneciphylline in which the hydroxy hydrogen is replaced by an acetyl group and the tertiary amino function is oxidised to the corresponding N-oxide.
    Acetylseneciphylline N-oxide
  • HY-N6849
    InteriotherinA 181701-06-4
    Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent.
    InteriotherinA
  • HY-N6938
    Pseudolaric acid B β-D-glucoside 98891-41-9
    Pseudolaric acid B β-D-glucoside is a diterpenoid isolated from Pseudolarix kaempferi.
    Pseudolaric acid B β-D-glucoside
  • HY-N6975
    Glyasperin D 142561-10-2 98%
    Glyasperin D is a flavonoid isolated from Glycyrrhiza uralensis, and possesses weaker anti-Helicobacter pylori activity.
    Glyasperin D
  • HY-N7003
    28-Demethyl-β-amyrone 73493-60-4 98%
    28-Demethyl-β-amyrone (28-Norolean-12-en-3-one) is one of the main triterpenes from Pistacia lentiscus var. Chia. 28-Demethyl-β-amyrone is an antitoxin and can effectively for the toxic effects of Staphylococcal enterotoxins (SEs).
    28-Demethyl-β-amyrone
  • HY-N7040
    11-Deoxymogroside IIE 2170761-38-1 98%
    11-Deoxymogroside IIE is a cucurbitane glycoside, isolated from Siraitia grosvenorii fruits. 11-Deoxymogroside IIE has inhibitory effect against Epstein Barr virus (EBV-EA) activation induced by TPA, shows weak inhibitory effect on (+/-)-(E)-methyl1-2-[E-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR1), a NO donor.
    11-Deoxymogroside IIE
  • HY-N7047
    8-Epidiosbulbin E acetate 91095-48-6 98.42%
    8-Epidiosbulbin E acetate, a furanoid, is abundant in Dioscorea bulbifera L.. 8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. 8-Epidiosbulbin E acetate induces liver injury in mice.
    8-Epidiosbulbin E acetate
  • HY-N7071
    Maduramicin 79356-08-4 98%
    Maduramicin (Maduramycin) is isolated from the actinomycete Actinomadura rubra. Maduramicin is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection. Maduramicin induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways.
    Maduramicin
  • HY-N7095
    Ceftezole 26973-24-0 98%
    Ceftezole (CTZ) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole (CTZ) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity.
    Ceftezole
  • HY-N7114
    Chloramphenicol succinate 3544-94-3 98%
    Chloramphenicol succinate is a prodrug of Chloramphenicol (HY-B0239), acting as a P2Y14R inhibitor with an IC50 of 1.585 nM. Chloramphenicol succinate serves as a competitive substrate and inhibitor of succinate dehydrogenase (SDH), which may account for its toxicity. Chloramphenicol succinate exerts a significant inhibitory effect on colitis. Chloramphenicol succinate can be used in research related to myelosuppression, gray baby syndrome, aplastic anemia, bacterial meningitis and inflammatory bowel disease.
    Chloramphenicol succinate
  • HY-N7118
    Clindamycin hydrochloride monohydrate 58207-19-5 98%
    Clindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla).
    Clindamycin hydrochloride monohydrate
  • HY-N7139
    Penicillin G 61-33-6 98%
    Penicillin G is a potent penicillinantibiotic. Penicillin G can be used for bacterial infection. Penicillin G has potent activity against all Gram-positive bacteria and Gram-negative cocci.
    Penicillin G
  • HY-N7173
    7-Methoxy-β-carboline-1-propionic acid 137756-13-9 98%
    7-Methoxy-β-carboline-1-propionic acid (compound 46) is a cytotoxic and antimalarial compound. 7-Methoxy-β-carboline-1-propionic acid can be extracted from the roots of Eurycoma longifolia.
    7-Methoxy-β-carboline-1-propionic acid
  • HY-N7194
    Yadanzioside L 99132-97-5 98%
    Yadanzioside L is a quassinoid and shows anti-tobacco mosaic virus (TMV) activity (IC50=4.86 μM).
    Yadanzioside L
  • HY-N7216
    Altromycin A 128439-47-4 98%
    Altromycin A is a natural Pluramycin-like antibacterial agent.
    Altromycin A
  • HY-N7218
    Lysolipin I 59113-57-4 98%
    Lysolipin I is a lipophilic antibiotic from Streptomyces violaceoniger. Lysolipin I is active against Gram-positive and Gramnegative bacteria.
    Lysolipin I
  • HY-N7221
    Janthitrem G 90986-51-9 98%
    Janthitrem G is a microbial metabolite that can be isolated from cultures of Penicillium.
    Janthitrem G
  • HY-N7222
    Janthitrem F 90986-52-0 98%
    Janthitrem F is a metabolite isolated from tremorigen-producing Penicillium and a potential causative agent of ryegrass spurt disease.
    Janthitrem F
  • HY-N7224
    N-Formylfortimicin A 74228-81-2 98%
    N-Formylfortimicin A (SF-1854) is an aminoglycoside antibiotic with broad-spectrum antibacterial activity. It primarily acts on bacterial ribosomes to inhibit protein synthesis and exhibits notable inhibitory effects against various Gram-positive and Gram-negative bacteria (e.g., E. coli with a MIC of 12.5-50 μg/mL), making it a potential candidate for research on bacterial infection-related diseases.
    N-Formylfortimicin A
Cat. No. Product Name / Synonyms Application Reactivity