2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N9036
    Drechslerine A 405157-84-8 98%
    Drechslerine A has neuraminidase inhibitory activity (IC50: 0.79 μM). Drechslerine A is a terpene that can be isolated from endophytic Cochliobolus. Drechslerine A can be used for research of Influenza Virus.
    Drechslerine A
  • HY-N9068
    Alterlactone 1030376-89-6 98%
    Alterlactone is an antimicrobial. Alterlactone shows broad antimicrobial activity against bacterial and fungal. Alterlactone has strong radical scavenging activity.
    Alterlactone
  • HY-N9087
    Filicenol B 145103-37-3 98%
    Filicenol B can be isolated from the whole plant of Adiantum lunulatum. Filicenol B has antibacterial activity.
    Filicenol B
  • HY-N9092
    Geranyl ferulate 1206615-69-1 98%
    Geranyl ferulate ((E)-geranylferulic acid), isolated from Zingiber officinale, exhibits inhibitory effect on the production of nitric oxide (NO).
    Geranyl ferulate
  • HY-N9179
    3′,4′,5′,5,6,7-Hexamethoxyflavone 29043-07-0 99.06%
    3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC50 of 21.3 μM (8.58 g/mL).
    3′,4′,5′,5,6,7-Hexamethoxyflavone
  • HY-N9194
    5-Methoxycanthin-6-one 15071-56-4 98%
    5-Methoxycanthin-6-one is an orally active inhibitor of Leishmania strains. 5-Methoxycanthin-6-one shows cytotoxicity with an IC50 of 5.44 μg/mL against Ailanthus altissima cells.
    5-Methoxycanthin-6-one
  • HY-N9229
    Myricadenin A 1612239-23-2 98%
    Myricadenin A is an iNOS inhibitor, capable of effectively inhibiting the production of NO (EC₅₀ = 18.1 μM). Myricadenin A has moderate ABTS free radical scavenging activity (SC₅₀ = 175.4 μM) and relatively weak anti-tuberculosis activity (MIC = 80.0 μg/mL). Myricadenin A can be used in inflammation-related research.
    Myricadenin A
  • HY-N9263
    Diacetylpiptocarphol 101628-29-9 98%
    Diacetylpiptocarphol (compound 4) is a sesquiterpene lactone compound. Diacetylpiptocarphol has anti-leishmaniasis activity .
    Diacetylpiptocarphol
  • HY-N9340
    Hypoglaunine D 220751-00-8 98%
    Hypoglaunine D is an analogue of Triptonine B and acts as an anti-HIV compound. Hypoglaunine D inhibits HIV replication in H9 lymphocytes with an EC50 value of 22 μg/ml.
    Hypoglaunine D
  • HY-N9367
    Soladulcidine 511-98-8 98%
    Soladulcidine, as an anticancer steroidal alkaloid, possesses antifungal and induction of congenital craniofacial malformation activities.
    Soladulcidine
  • HY-N9370
    Isobellidifolin 552-00-1 98%
    Isobellidifolin, a xanthone, is a free radical scavenger and antioxidant compound. Isobellidifolin has potent antifungal effect.
    Isobellidifolin
  • HY-N9378
    3-Oxobetulin 7020-34-0 98%
    3-Oxobetulin, an antifungal agent, shows antifungal activities against white rot fungus L. betulina and the brown rot fungus L. sulphureus.
    3-Oxobetulin
  • HY-N9475
    Betulonaldehyde 4439-98-9 98%
    Betulonaldehyde is a pentacyclic triterpenoid that can be isolated from Diospyros filipendula. Betulonaldehyde has antiplasmodial activity (IC50: 3.36 µg/mL). Betulonaldehyde has cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s: 19.23 and 17.09 µg/mL, respectively). Betulonaldehyde inhibits Phorbol 12-myristate 13-acetate (HY-18739) induced inflammation in mice.
    Betulonaldehyde
  • HY-N9530
    1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone 120693-53-0 98%
    1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a quinolone alkaloid, is a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, with IC50s of 20.1 μM and 34.1 μM, respectively. 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone shows potent anti-Helicobacter pylori activity with the MIC of 10 μg/mL.
    1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone
  • HY-N9531
    3'-Hydroxyxanthyletin 165900-08-3 98%
    3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities.
    3'-Hydroxyxanthyletin
  • HY-N9564
    Pisatin 469-01-2 98%
    Pisatin is a phytoalexin found in pea (Pisum sativum L.) and an anti-fungal agent. Pisatin can be used for the research of pea plant disease caused by Nectria haematococca.
    Pisatin
  • HY-N9574
    Oleoside dimethylester 30164-95-5 98%
    Oleoside dimethylester is a secoiridoid glucoside found in the fruits of Ligustrum lucidum. Oleoside dimethylester exhibits inhibitory activity against type 3 parainfluenza virus (Para 3) and respiratory syncytial virus (RSV), with IC50 values of 20.8 and 83.2 μg/mL. Oleoside dimethylester also shows antioxidant effect.
    Oleoside dimethylester
  • HY-N9615
    Azadiradione 26241-51-0 98%
    Azadiradione is a bioactive limonoid found in Azadirachta indica. Azadiradione is a HSF1 activator. Azadiradione has antimycobacterial, anti-nociceptive and anti-inflammatory activities.
    Azadiradione
  • HY-N9664
    Crepidiaside B 101921-35-1 98%
    Crepidiaside B is a plant-derived active component that can be found in Cichorium intybus. Crepidiaside B acts as a SARS-CoV-2 spike glycoprotein inhibitor and is used in research related to coronavirus disease 2019 (COVID-19).
    Crepidiaside B
  • HY-N9666
    Chromomycin A4 7198-11-0 98%
    Chromomycin A4, a major byproduct of Chromomycin A3 (HY-W040129)'s manufacture, is an antibiotic produced by Streptomyces griseus No. 7. Chromomycin A4 exhibits cancerostatic and antitumor activity. Chromomycin A4 shows strong growth inhibition against Gram-positive bacteria and and activity against tuberculous bacilli. Chromomycin A4 can be used for the research of bacterial infection.
    Chromomycin A4
Cat. No. Product Name / Synonyms Application Reactivity