5-Methoxycanthin-6-one
5-Methoxycanthin-6-one is an orally active inhibitor of Leishmania strains. 5-Methoxycanthin-6-one shows cytotoxicity with an IC50 of 5.44 μg/mL against Ailanthus altissima cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 15071-56-4
- 分子式: C15H10N2O2
- 分子量:250.25
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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Leishmania |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | ED50 |
3.1 μg/mL
Compound: 6
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Cytotoxicity against human A549 cells after 3 days by SRB assay
Cytotoxicity against human A549 cells after 3 days by SRB assay
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[PMID: 11141127] |
| CAKI-1 | ED50 |
4.4 μg/mL
Compound: 6
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Cytotoxicity against human CAKI1 cells after 3 days by SRB assay
Cytotoxicity against human CAKI1 cells after 3 days by SRB assay
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[PMID: 11141127] |
| HCT-8 | ED50 |
2.5 μg/mL
Compound: 6
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Cytotoxicity against human HCT8 cells after 3 days by SRB assay
Cytotoxicity against human HCT8 cells after 3 days by SRB assay
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[PMID: 11141127] |
| KB | ED50 |
2.9 μg/mL
Compound: 6
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Cytotoxicity against human KB cells after 3 days by SRB assay
Cytotoxicity against human KB cells after 3 days by SRB assay
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[PMID: 11141127] |
| MCF7 | ED50 |
5 μg/mL
Compound: 6
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Cytotoxicity against human MCF7 cells after 3 days by SRB assay
Cytotoxicity against human MCF7 cells after 3 days by SRB assay
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[PMID: 11141127] |
| SK-MEL-2 | ED50 |
17 μg/mL
Compound: 6
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Cytotoxicity against human SK-MEL-2 cells after 3 days by SRB assay
Cytotoxicity against human SK-MEL-2 cells after 3 days by SRB assay
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[PMID: 11141127] |
化学情報
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CAS 番号 15071-56-4
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分子量 250.25
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分子式 C15H10N2O2
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SMILES
O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4)C=C1OC
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Ferreira ME, et al. Leishmanicidal activity of two canthin-6-one alkaloids, two major constituents of Zanthoxylum chiloperone var. angustifolium. J Ethnopharmacol. 2002 May;80(2-3):199-202. [Content Brief]
[2]. Anderson LA, et al. Production of cytotoxic canthin-6-one alkaloids by Ailanthus altissima plant cell cultures. J Nat Prod. 1983 May-Jun;46(3):374-8. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
5-Methoxycanthin-6-one 関連分類
HY-N9194 関連分類
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