15071-56-4
15071-56-4
Chemical Structure
5-Methoxycanthin-6-one
- CAS. Nr.: 15071-56-4
- Formula:C15H10N2O2
- Molecular Weight:250.25
IUPAC Name: 5-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
InChIKey: TXEFUSAHPIYZHD-UHFFFAOYSA-N
SMILES: O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4)C=C1OC
Biological Activity: 5-Methoxycanthin-6-one is an orally active inhibitor of Leishmania strains. 5-Methoxycanthin-6-one shows cytotoxicity with an IC50 of 5.44 μg/mL against Ailanthus altissima cells[1][2].
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5-Methoxycanthin-6-one | 5-Methoxycanthin-6-one is an orally active inhibitor of Leishmania strains. 5-Methoxycanthin-6-one shows cytotoxicity with an IC50 of 5.44 μg/mL against Ailanthus altissima cells. | |||||||||||||||||||||
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References
- [1]. Ferreira ME, et al. Leishmanicidal activity of two canthin-6-one alkaloids, two major constituents of Zanthoxylum chiloperone var. angustifolium. J Ethnopharmacol. 2002 May;80(2-3):199-202. [Content Brief]
- [2]. Anderson LA, et al. Production of cytotoxic canthin-6-one alkaloids by Ailanthus altissima plant cell cultures. J Nat Prod. 1983 May-Jun;46(3):374-8. [Content Brief]
Keywords
