2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N10212
    Dendryphiellin D 121678-87-3 98%
    Dendryphiellin D is a compound isolated from fungus Septoria rudbeckiae, a plant pathogenic fungus isolated from the halophyte Karelinia caspia. Dendryphiellin D significantly inhibits the production of nitric oxide (NO).
    Dendryphiellin D
  • HY-N10213
    Septeremophilane E 98%
    Septeremophilane E is a compound isolated from fungus Septoria rudbeckiae, a plant pathogenic fungus isolated from the halophyte Karelinia caspia. Septeremophilane E significantly inhibits the production of nitric oxide (NO).
    Septeremophilane E
  • HY-N10215
    Canadensolide 20421-31-2 98%
    Canadensolide is an antifungal metabolite of Penicillium canadense.
    Canadensolide
  • HY-N10216
    Cynodontin 476-43-7 98%
    Cynodontin is a metabolic product of Helminthosporium cynodontis Marignoni and Helminthosporium euchlaenae Zimmermann.
    Cynodontin
  • HY-N10219
    Dihydroaltenuene B 887751-89-5 98%
    Dihydroaltenuene B is a potent mushroom tyrosinase inhibitor with an IC50 of 38.33 µM. Dihydroaltenuene B shows the hydrogen bonding interactions between the 3-OH and 4’-OH and the His244, Met280 and Gly281 residues of tyrosinase.
    Dihydroaltenuene B
  • HY-N10222
    Roquefortine E 871982-52-4 98%
    Roquefortine E is a diketopiperazine from an Australian isolate of Gymnoascus reessii.
    Roquefortine E
  • HY-N10227
    Geodin 427-63-4 98%
    Geodin, a fungal metabolite, shows antibacterial activity. Geodin also is an inhibitor of plasminogen activator inhibitor- 1 (PAI-1).
    Geodin
  • HY-N10228
    Gliorosein 4373-40-4 98%
    Gliorosein is a fungal metabolite isolated from Gliocladium. Gliorosein is isomeric with the quinol but shows a different ultraviolet absorption spectrum.
    Gliorosein
  • HY-N10230
    MC 304 124709-28-0 98%
    MC 304 is a β-resorcylate isolated from cultures of Phanerochaete chrysosporium. MC 304 has antibacterial activity. MC 304 shows a stimulatory effect on root elongation of Lepidium satiuum.
    MC 304
  • HY-N10231
    Agistatin D 144096-47-9 98%
    Agistatin D is a pyranacetal originally isolated from a Fusarium sp. that inhibits the cholesterol biosynthesis.
    Agistatin D
  • HY-N10232
    Agistatin E 144096-48-0 98%
    Agistatin E is a pyranacetal originally isolated from a Fusarium sp. that inhibits the cholesterol biosynthesis.
    Agistatin E
  • HY-N10233
    6-Ethyl-2,7-dimethoxyjuglone 15254-86-1 98%
    6-Ethyl-2,7-dimethoxyjuglone is a metabolite isolated from freshwater fungi.
    6-Ethyl-2,7-dimethoxyjuglone
  • HY-N10234
    Phenylpyropene A 189564-20-3 98%
    Phenylpyropene A, a fungal metabolite, is a potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with an IC50 of 0.8 μM.
    Phenylpyropene A
  • HY-N10236
    Carbolactone 155443-55-3 98%
    Carbolactone is a biologically active metabolite from fungi.
    Carbolactone
  • HY-N10255
    Trypacidin 1900-29-4 98%
    Trypacidin is the conidia-bound metabolite with antiprotozoal activity. Trypacidin has a protective function against phagocytes both in the environment and during the infection process.
    Trypacidin
  • HY-N10256
    Varioxepine A 1623451-72-8 98%
    Varioxepine A is a 3H-oxepine-containing alkaloid with a new oxa-cage found in the marine algal-derived endophytic fungus Paecilomyces variotii. Varioxepine A inhibits plant pathogenic fungus Fusarium graminearum.
    Varioxepine A
  • HY-N10258
    (+)-Sorokinianin 162616-73-1 98%
    (+)-Sorokinianin is a phytotoxin from an isolate of Bipolaris sorokiniana.
    (+)-Sorokinianin
  • HY-N10259
    Norfunalenone 581786-63-2 98%
    Norfunalenone exhibits weak cytotoxic activity in mouse myeloma NS-1 cell line (ATCC TIB-18) with an IC50 of 70 μM. Norfunalenone also exhibits weak antibacterial activity against B. subtilis (MIC=100 μg/mL; IC50=265 μM).
    Norfunalenone
  • HY-N10263
    Palmarumycin C3 159934-11-9 98%
    Palmarumycin C3 is a spirobisnaphthalene compound isolated from cultures of the endophytic fungus Berkleasmium sp. Dzf12 after treatment with 1-hexadecene. Palmarumycin C3 exhibits stronger antimicrobial and antioxidant activities.
    Palmarumycin C3
  • HY-N10267
    Carviolin 478-35-3 98%
    Carviolin is a compound isolated from the mycelia of the ascomycete Neobulgaria pura. Carviolin inhibits the formation of appressoria in germinating conidia of Magnaporthe grisea on inductive (hydrophobic) surface. Carviolin exhibits moderate cytotoxic, but no antifungal, antibacterial, or phytotoxic activities.
    Carviolin
Cat. No. Product Name / Synonyms Application Reactivity