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Cat. No.: HY-N10267

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Carviolin

Carviolin is a compound isolated from the mycelia of the ascomycete Neobulgaria pura. Carviolin inhibits the formation of appressoria in germinating conidia of Magnaporthe grisea on inductive (hydrophobic) surface. Carviolin exhibits moderate cytotoxic, but no antifungal, antibacterial, or phytotoxic activities.

For research use only. We do not sell to patients.

CAS No.: 478-35-3
Formula: C₁₆H₁₂O₆
Molecular Weight:300.26

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Carviolin Chemical Structure

CAS No.: 478-35-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
Jurkat	IC₅₀	>100 μM Compound: 9	Cytotoxicity against human Jurkat cells after 24 hrs by MTT assay Cytotoxicity against human Jurkat cells after 24 hrs by MTT assay	[PMID: 21146414]
K562	IC₅₀	>100 μM Compound: 9	Inhibition of NF-kappaB activity in TNFalpha-stimulated human K562 cells after 24 hrs by luciferase reporter gene assay Inhibition of NF-kappaB activity in TNFalpha-stimulated human K562 cells after 24 hrs by luciferase reporter gene assay	[PMID: 21146414]
U-937	IC₅₀	>100 μM Compound: 9	Cytotoxicity against human U937 cells after 24 hrs by MTT assay Cytotoxicity against human U937 cells after 24 hrs by MTT assay	[PMID: 21146414]

Chemical Information

CAS No. 478-35-3
Molecular Weight 300.26
Formula C₁₆H₁₂O₆
SMILES

O=C1C2=C(C=C(CO)C=C2OC)C(C3=CC(O)=CC(O)=C13)=O
Structure Classification
- Quinones
- Anthraquinones
- Phenols
- Polyphenols
Initial Source
- Microorganisms
Penicillium dravuni
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Eilbert F, et al. Neobulgarones A approximately F from cultures of Neobulgaria pura, new inhibitors of appressorium formation of Magnaporthe grisea. J Antibiot (Tokyo). 2000;53(10):1123-1129. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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