2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W145053
    ChloraMine-T hydrate 149358-73-6 98.18%
    ChloraMine-T hydrate (Sodium chloro(4-methylbenzenesulfonyl)azanide (hydrate)) is a common reagent in various synthetic processes. It has been used as a reagent in aminohydroxylation and allylic amination reactions, a nitrogen source in aziridination reactions of alkenes and alkenes, and deprotection of sulfur groups in sulfur-containing compounds. It has been used as a reagent in the synthesis of factor Xa inhibitors. ChloraMine-T hydrate (Sodium chloro(4-methylbenzenesulfonyl)azanide (hydrate)) (0.2% w/v) is also an antimicrobial agent that kills Staphylococcus epidermidis, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Proteus mirabilis, and Enterococcus cloacae.
    ChloraMine-T hydrate
  • HY-W150903
    N-Heptyl 4-hydroxybenzoate 1085-12-7 99.60%
    N-Heptyl 4-hydroxybenzoate (p-Oxybenzoesaureheptylester) is an antimicrobial agent that inhibits S. aureus with MIC of 12.5 μg/mL. N-Heptyl 4-hydroxybenzoate also against plant pathogenic fungi, such as Alternaria brassicicola, F. solani, C. dematium and C. acutatum.
    N-Heptyl 4-hydroxybenzoate
  • HY-W154247
    IP6C 103313-38-8 98%
    IP6C is a specific inhibitor and phage sensitizer targeting type II Thoeris systems. IP6C competitively binds to histidine in the catalytic pocket of ThsB, blocks the production of the His-ADPR alarm signal and inhibits ThsA activation, thereby relieving bacterial stasis of phage replication. IP6C selectively resensitizes drug-resistant bacteria carrying type II Thoeris systems (such as Pseudomonas aeruginosa) to phage lysis, without affecting other bacteria, and shows no toxicity to mice and human cell lines. IP6C significantly improves the survival rate of infected mice, and can be used to overcome bacterial phage defense mechanisms and study Pseudomonas aeruginosa infections.
    Thoeris system: (named after the Egyptian goddess of fertility and protection), is a widespread anti-phage immune defense system in bacteria and archaea. Thoeris system belongs to the "Abortion Infection (Abi)" mechanism of bacteria: when an individual bacterium detects phage invasion, it initiates a suicide program and dies, thereby blocking phage replication and spread, and protecting the surrounding bacterial population from infection.
    IP6C
  • HY-W158616
    3-Methyl-1-hexanol 13231-81-7 98.0%
    3-Methyl-1-hexanol, a volatile organic compound, is a microbial antagonist that can be isolated from Aureobasidium pullulans. 3-Methyl-1-hexanol has antifungal activities against Alternaria alternate and Botrytis cinerea. 3-Methyl-1-hexanol can be used for microbial infections research.
    3-Methyl-1-hexanol
  • HY-W159102
    8CN 40106-14-7 98%
    8CN, a 2-amino-thiophene derivative, has anti-leishmanial activity. 8CN can be used in research of Leishmaniasis.
    8CN
  • HY-W160358
    2,5-Dimethylcyclohexanol 3809-32-3 99.88%
    2,5-Dimethylcyclohexanol, a volatile organic compound, is a fatty acid that can be isolated from Amphora sp.. 2,5-Dimethylcyclohexanol has significant antineoplastic and antiviral activities with inhibition of SARS-CoV-2 Mpro. 2,5-Dimethylcyclohexanol also has potent antifungal activity against Pseudogymnoascus destructans. 2,5-Dimethylcyclohexanol compromises cell wall and membrane integrity while perturbing energy metabolism, increases the levels of ROS, ATP, Superoxide anion and GSH, and decreases CAT and SOD activities. And 2,5-Dimethylcyclohexanol alters virulence ribosomal genes expression, and disrupts the MAPK signaling pathways, inducing fungal cell apoptosis.
    2,5-Dimethylcyclohexanol
  • HY-W164451
    N-(2-hydroxy-2-phenylethyl)acetamide 3306-05-6 98%
    N-(2-hydroxy-2-phenylethyl)acetamide is isolated from the solid rice cultures of the endophytic fungus Diaporthe eucalyptorum KY-9. N-(2-hydroxy-2-phenylethyl)acetamide exhibits antifungal activities against Alternaria solani.
    N-(2-hydroxy-2-phenylethyl)acetamide
  • HY-W167398
    Phenosulfazole 515-54-8 98%
    Phenosulfazole is an effective antiviral agent. Phenosulfazole has the potential for the research of poliomyelitis virus.
    Phenosulfazole
  • HY-W169645
    1,5-Hexadien-3-ol 924-41-4 98%
    1,5-Hexadien-3-ol is a green leaf volatile (GLV) alcohol that can be found in tomato plants. 1,5-Hexadien-3-ol contributes to protection against Botrytis cinerea. 1,5-Hexadien-3-ol can be used for the research of grey mould disease.
    1,5-Hexadien-3-ol
  • HY-W197393
    3,6-Diaminoacridine sulfate 553-30-0 98%
    Proflavine sulfate is a multifunctional acridine compound. 3,6-Diaminoacridine sulfate is an acridine dye and also a DNA inserter. Proflavine sulfate is a potent broad-spectrum antibacterial agent, and its mechanism is to insert into bacterial DNA, interfering with replication and transcription, causing bacterial lysis. 3,6-Diaminoacridine sulfate is a Kir3.2 potassium channel blocker and can be used to study the neurological phenotype of Down syndrome. 3,6-Diaminoacridine sulfate can penetrate the stratum corneum of the skin and accumulate in the cell nucleus and long-term exposure may induce skin cancer or other malignant tumors.
    3,6-Diaminoacridine sulfate
  • HY-W202230
    Buclosamide 575-74-6 98%
    Buclosamide is a topical antimycotic agent.
    Buclosamide
  • HY-W247616
    (4-Aminobenzyl)phosphonic acid 5424-27-1 98.0%
    (4-Aminobenzyl)phosphonic acid is a bioactive compound with potential anticancer and antibacterial activities. (4-Aminobenzyl)phosphonic acid is widely used in compound synthesis to develop new inhibition methods. Through its unique structure, (4-Aminobenzyl)phosphonic acid can effectively interact with biological targets.
    (4-Aminobenzyl)phosphonic acid
  • HY-W268334
    1,2,3,4-Tetrahydronorharman-1-one 17952-82-8 98%
    1,2,3,4-Tetrahydronorharman-1-one is a manzamine alkaloid with activity against infectious and tropical parasitic diseases from an Indonesian sponge.
    1,2,3,4-Tetrahydronorharman-1-one
  • HY-W272811
    Camphorsulfonate sodium 34850-66-3 98%
    Camphorsulfonate sodium is an organic synthesis intermediate. Camphorsulfonate sodium can be used for synthesis of derivatives with SDH inhibitory activity through scaffold hopping. Camphorsulfonate sodium is also an organocatalyst that can be used as a pore-forming additive for modulating the porosity of the graphene film. Camphorsulfonate sodium can be used for binder-free porous graphene film and fungicide research.
    Camphorsulfonate sodium
  • HY-W278232
    Urease-IN-6 362502-79-2 98.89%
    Urease-IN-6 is a potent inhibitor of Urease with an IC50 of 14.2 μM. Urease-IN-6 can be used in study peptic and gastric ulcers .
    Urease-IN-6
  • HY-W280349
    1-Phenylsemicarbazide 103-03-7
    1-Phenylsemicarbazide is an antifungal agent. 1-Phenylsemicarbazide has the potential for preventing mold growth on industrial products.
    1-Phenylsemicarbazide
  • HY-W282615
    Antibacterial agent 117 341944-06-7 98.01%
    Antibacterial agent 117, triazole derivative, is an antibacterial agent. Antibacterial agent 117 has against R. prowazekii MetAP1 (RpMetAP1) activity with an IC50 value of 15 μM. Antibacterial agent 117 also inhibits rickettsial growth and can be used for the research of infection.
    Antibacterial agent 117
  • HY-W317470
    2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl cyanide 23316-67-8 98%
    2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl cyanide is a nucleoside analogue with the activity of inhibiting viral replication and inhibiting tumor growth. 2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl cyanide is mainly used in nucleoside synthesis to interfere with biological processes in cells. 2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl cyanide shows potential application value in antiviral and antitumor research.
    2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl cyanide
  • HY-W319332
    Necrostatin-21 169136-33-8 98%
    Necrostatin-21 (Compound Nec-21) is a necroptosis inhibitor with an EC50 of 0.5 μM. Necrostatin-21 has a dual inhibitory effect on the RIP1 and JNK3 kinases. Necrostatin-21 can be used for the researches of infection, cardiovascular and neurological disease, such as Alzheimer disease .
    Necrostatin-21
  • HY-W320523
    ALizarin complexone dihydrate 455303-00-1 98%
    ALizarin complexone dihydrate is the dehydrate of Alizarin complexone (HY-121075). Alizarin complexone is a calcium-binding fluorescent dye. Alizarin complexone stains mineralized areas of bone by binding to calcium crystals. Alizarin complexone inhibits the reverse transcriptase activity of RAV-2, HIV-1, and RSV with IC50 values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. Alizarin complexone exhibits antiviral activity against HIV-1 and RSV. Alizarin complexone delays RSV-induced tumor induction in chickens.
    ALizarin complexone dihydrate
Cat. No. Product Name / Synonyms Application Reactivity