1. Infection

Infection

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W725476
    Bifenazate-d5 98%
    Bifenazate-d5 is the deuterium labeled Bifenazate (HY-119687). Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm. Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is the inhibitor for the mitochondrial electron transport chain complex III.
    Bifenazate-d5
  • HY-W725641
    Tricyclazole-d3 98%
    Tricyclazole-d3 is the deuterium labeled Tricyclazole. Tricyclazole is a pentaketide-derived melanin biosynthesis inhibitor.
    Tricyclazole-d3
  • HY-W725955
    Fostemsavir sodium 864953-31-1 98%
    Fostemsavir sodium (BMS-663068 sodium) is an HIV-1 attachment inhibitor with antiviral activity against multidrug-resistant HIV-1. Co-inhibition with fostemsavir sodium also showed a trend toward reduction in markers of monocyte activation and coagulation abnormalities.
    Fostemsavir sodium
  • HY-W727391
    β-Calacorene 50277-34-4 98%
    β-calacorene is an essential oil metabolite. β-calacorene shows AMES toxicity or mutagenic potential. β-calacorene can be used in the research of Staphylococcus aureus infections.
    β-Calacorene
  • HY-W727466
    4,6-Dimethyldodecane 61141-72-8 98%
    4,6-Dimethyldodecane is an alkane. 4,6-Dimethyldodecane can be derived from the oil of T. decandra. 4,6-Dimethyldodecane can be used in bacterial infection research.
    4,6-Dimethyldodecane
  • HY-W738270
    Veratraldehyde-13C 1173022-44-0 98%
    Veratraldehyde-13C (3,4-Dimethoxy[7-13C]-benzaldehyde) is the 13C-labeled Veratraldehyde (HY-N1096). Veratraldehyde is an orally active aromatic compound and antibacterial agent. Veratraldehyde can be isolated from essential oils of plants such as peppermint and ginger. Veratraldehyde targets the PilY1 protein. Veratraldehyde has antibacterial activity against Pseudomonas aeruginosa. Veratraldehyde has a repellent effect against mosquitoes and ticks. Veratraldehyde can be used as a flavoring agent.
    Veratraldehyde-13C
  • HY-W738271
    Veratryl alcohol-13C 91384-88-2 98%
    Veratryl alcohol-13C (3,4-Dimethoxybenzyl alcohol-13C) is the 13C-labeled Veratryl alcohol (HY-107858). Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy.
    Veratryl alcohol-13C
  • HY-W738281
    Chlorhexidine-d8 1246816-96-5 98%
    Chlorhexidine-d8 is deuterium-labeled Chlorhexidine (HY-B1248). Chlorhexidine is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis).
    Chlorhexidine-d8
  • HY-W739223
    Trans-Cinnamic acid-d6 98%
    Trans-Cinnamic acid-d6 (Trans-3-Phenylacrylic acid-d6) is the deuterium labeled Trans-Cinnamic acid (HY-N0610). trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1.
    Trans-Cinnamic acid-d6
  • HY-W739267
    Fenazaquin-d13 98%
    Fenazaquin-d13 (XDE-436-d13) is the deuterium labeled Fenazaquin (HY-117397). Fenazaquin (XDE-436; EL-436) is a quinazoline acaricide.
    Fenazaquin-d13
  • HY-W740048
    Quinine-d3 2734920-95-5 98%
    Quinine-d3 is the deuterium labeled Quinine (HY-D0143). Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM.
    Quinine-d3
  • HY-W740053
    Meropenem sodium 211238-34-5 98%
    Meropenem sodium is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem sodium has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL).
    Meropenem sodium
  • HY-W740297
    Methyl Clonazepam-d3 1189992-73-1 98%
    Methyl Clonazepam-d3 is the deuterium labeled Methylclonazepam (HY-W399186). Methylclonazepam is a benzodiazepine with anxiolytic activity. Methylclonazepam inhibits the absorption of 5-hydroxytryptamine by Schistosoma mansoni. Methylclonazepam derivatives have anti-Schistosoma mansoni activity.
    Methyl Clonazepam-d3
  • HY-W740485
    Hexamidine-d12 1286461-12-8 98%
    Hexamidine-d12 is the deuterium labeled Hexamidine. Hexamidine has amoebicidal effect that can be used for the research of Acanthamoeba keratitis.
    Hexamidine-d12
  • HY-W740651
    Jasmolin II 1172-63-0 98%
    Jasmolin II is an insecticide targeting voltage-gated sodium channels in insects. Jasmolin II leads to neuronal hyperexcitation and insect paralysis. Jasmolin II is promising for research of agricultural pests.
    Jasmolin II
  • HY-W740833
    Iodopropynyl butylcarbamate-d9 1246815-08-6 98%
    Iodopropynyl butylcarbamate-d9 (IPBC-d9) is the deuterium labeled Iodopropynyl butylcarbamate (HY-W009335). Iodopropynyl butylcarbamate (IPBC) is a potent fungicide and preservative, which has been used in the paints, coatings, wood preservatives, personal care, and cosmetics industries.
    Iodopropynyl butylcarbamate-d9
  • HY-W741748
    Desacetylcephapirin-d6 sodium 98%
    Desacetylcephapirin-d6 sodium (Deacetylcephapirin-d6 sodium) is the deuterium labeled Desacetylcephapirin sodium (HY-131989). Desacetylcephapirin (Deacetylcephapirin) sodium is an active metabolite of Cephapirin (HY-A0153A). Desacetylcephapirin sodium has antimicrobial against S. aureus and coagulase-negative staphylococci mastitis pathogen.
    Desacetylcephapirin-d6 sodium
  • HY-W741987
    6,7-Dehydro Norethindrone 31528-46-8 98%
    6,7-Dehydro Norethindrone (6,7-Didehydronorethisterone) (Compound 26) is a Norethisterone (HY-B0554) metabolite. 6,7-Dehydro Norethindrone can be produced by the biotransformation of Norethisterone using Rhizopus microsporus PT2906. 6,7-Dehydro Norethindrone induces Apoptosis, binds to p53 and inhibits the degradation of p53. 6,7-Dehydro Norethindrone selectively exhibits antitumor activity against cervical cancer.
    6,7-Dehydro Norethindrone
  • HY-W742895
    Tildipirosin-d10 98%
    Tildipirosin-d10 is the deuterium labeled Tildipirosin (HY-A0071). Tildipirosin, a long-acting?macrolide, has?antibiotic?activity.
    Tildipirosin-d10
  • HY-W743292
    Phenethicillin sodium-d5 98%
    Phenethicillin sodium-d5 (Pheneticillin sodium-d5; α-Phenoxyethylpenicillin sodium-d5) is the deuterium labeled Phenethicillin sodium (HY-137945). Phenethicillin (α-Phenoxyethylpenicillin) sodium is a Penicillin, and has antimicrobial activity.
    Phenethicillin sodium-d5
Cat. No. Product Name / Synonyms Application Reactivity