Bifenazate-d5
Based on 1 Customer Validation
Bifenazate-d5 is the deuterium labeled Bifenazate (HY-119687). Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm. Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is the inhibitor for the mitochondrial electron transport chain complex III.
For research use only. We do not sell to patients.
- Formula: C17H15D5N2O3
- Molecular Weight:305.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 149877-41-8
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Molecular Weight 305.38
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Formula C17H15D5N2O3
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SMILES
COC(C=CC(C1=C(C([2H])=C(C([2H])=C1[2H])[2H])[2H])=C2)=C2NNC(OC(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[2]. Hiragaki S, et al. A novel action of highly specific acaricide; bifenazate as a synergist for a GABA-gated chloride channel of Tetranychus urticae [Acari: Tetranychidae]. Neurotoxicology. 2012 Jun;33(3):307-13. [Content Brief]
[3]. Ma J, et al., Bifenazate exposure induces cardiotoxicity in zebrafish embryos. Environ Pollut. 2021 Apr 1;274:116539. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)