1. Anti-infection
  2. Penicillin-binding protein (PBP) Bacterial Antibiotic
  3. Meropenem sodium

Meropenem sodium is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem sodium has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL).

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CAS No. : 211238-34-5

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Based on 28 publication(s) in Google Scholar

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28 Publications Citing Use of MCE Meropenem sodium

Bio/Physico-chemical Assay
Microbiological Assay

    Meropenem sodium purchased from MedChemExpress. Usage Cited in: mLife. 2025 Apr 15;4(2):155-168.  [Abstract]

    Treatment of wild-type BCG with the ClpP-targeting compound GDI-5755 and Ethambutol (ETH) or Meropenem (MPM) significantly reduced the minimum inhibitory concentration (MIC) of each drug.

    Meropenem sodium purchased from MedChemExpress. Usage Cited in: BMC Microbiol. 2025 Apr 29;25(1):257.  [Abstract]

    To evaluate the influence of various concentrations of xylose on the antimicrobial susceptibility of K. pneumoniae, the MIC values of K. pneumoniaetoward commonly used antibiotics, including Meropenem, Gentamicin, and Ceftriaxone, were determined after xylose exposure at various concentrations.

    Meropenem sodium purchased from MedChemExpress. Usage Cited in: Emerg Microbes Infect. 2024 Dec;13(1):2321981.  [Abstract]

    Antibacterial activity of AMXT-1501 against K. pneumoniae, an ESBL-producing E. coli, and carbapenem-resistant Enterobacteriaceae E. coli detected by time-killing assays; compared with meropenem or tigecycline (final concentration at 8× MIC); The dashed lines indicated the limit of detection of time-killing assays. Antibacterial activity of AMXT-1501 against abdominal infected with E. coli ECO2219 (n = 15/group); compared with TIG.

    Meropenem sodium purchased from MedChemExpress. Usage Cited in: Microorganisms. 2024 Mar 13;12(3):575.

    Percentages of E. coli strains showing antimicrobial resistance to different antimicrobial agents. AMP, Ampicillin; CAZ, Ceftazidime; IPM, Imipenem; MRP, Meropenem; GEN, Gentamicin; OFX, Ofloxacin; SXT, Trimethoprim–sulfamethoxazole; TET, Tetracycline; TGC, Tigecycline; CL, Colistin; FFC, Florfenicol.

    Meropenem sodium purchased from MedChemExpress. Usage Cited in: Open Forum Infect Dis. 2023 Jan 27;10(2):ofad038.

    Ceftazidime-avibactam, Meropenem, and Imipenem were the most active β-lactam agents tested against 2663 ESBL-producing E. coli and K. pneumoniae isolates that were carbapenem susceptible

    Meropenem sodium purchased from MedChemExpress. Usage Cited in: Nat Commun. 2022 Mar 2;13(1):1116.  [Abstract]

    Resistance rates of Escherichia coli isolates from farms in different provinces of mainland China to different classes of antibiotics, including Meropenem.

    Meropenem sodium purchased from MedChemExpress. Usage Cited in: J Antimicrob Chemother. 2020 Jul 1;75(7):1850-1858.  [Abstract]

    The cumulative MIC distributions of Cefepime/Taniborbactam, Ceftazidime/Avibactam and comparator Meropenem for 500 tested isolates. The MICs of cefepime and Cefepime/Taniborbactam shown in the figure were tested by the broth microdilution method. The MICs of Meropenem shown in the figure were tested by the agar dilution method. SS, susceptible to all tested β-lactams. SS-P. aeruginosa, meropenem-susceptible P. aeruginosa. Nine IMP producers included three blaIMP-producing P. aeruginosa.
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    Description

    Meropenem sodium is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem sodium has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2].

    Molecular Weight

    405.44

    Formula

    C17H24N3NaO5S

    CAS No.
    SMILES

    O=C(C1=C(S[C@H]2C[C@H](NC2)C(N(C)C)=O)[C@H](C)[C@@]([C@@]3([H])[C@H](O)C)([H])N1C3=O)O[Na]

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    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
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